Comparative characterization of oxidative stress in cervical cancer at different clinical stages of disease
Parameters of oxidative stress on the level of malondialdehyde (MDA), activity of glutathione-reductase, glutathione-transferase, superoxide- dismutase (SOD) and catalase in tumor tissue, plasma and red blood cells of patients with cervical cancer (CC) w as evaluated a t various clinical stages of t...
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| Format: | Article |
| Language: | Russian |
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ABV-press
2014-08-01
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| Series: | Опухоли женской репродуктивной системы |
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| Online Access: | https://ojrs.abvpress.ru/ojrs/article/view/198 |
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| author | I. I. Antoneeva T. P. Gening D. R. Arslanova E. G. Sidorenko |
| author_facet | I. I. Antoneeva T. P. Gening D. R. Arslanova E. G. Sidorenko |
| author_sort | I. I. Antoneeva |
| collection | DOAJ |
| description | Parameters of oxidative stress on the level of malondialdehyde (MDA), activity of glutathione-reductase, glutathione-transferase, superoxide- dismutase (SOD) and catalase in tumor tissue, plasma and red blood cells of patients with cervical cancer (CC) w as evaluated a t various clinical stages of the disease. It is revealed that an increase in tumor tissue MD A and glutathione enzymes while reducing SOD and catalase, which may indicate the development of oxidative stress in the dynamics of tumor progression. The data obtained suggest the increase of expres- sion of oxidative stress in red blood cells and tumor tissue in CC in the dynamics of tumor progression. |
| format | Article |
| id | doaj-art-3e8f2ab5e508452087ea6902e95e465e |
| institution | DOAJ |
| issn | 1994-4098 1999-8627 |
| language | Russian |
| publishDate | 2014-08-01 |
| publisher | ABV-press |
| record_format | Article |
| series | Опухоли женской репродуктивной системы |
| spelling | doaj-art-3e8f2ab5e508452087ea6902e95e465e2025-08-20T03:02:01ZrusABV-pressОпухоли женской репродуктивной системы1994-40981999-86272014-08-0104555810.17650/1994-4098-2011-0-4-55-58214Comparative characterization of oxidative stress in cervical cancer at different clinical stages of diseaseI. I. Antoneeva0T. P. Gening1D. R. Arslanova2E. G. Sidorenko3Ulyanovsk State UniversityUlyanovsk State UniversityUlyanovsk State UniversityUlyanovsk State UniversityParameters of oxidative stress on the level of malondialdehyde (MDA), activity of glutathione-reductase, glutathione-transferase, superoxide- dismutase (SOD) and catalase in tumor tissue, plasma and red blood cells of patients with cervical cancer (CC) w as evaluated a t various clinical stages of the disease. It is revealed that an increase in tumor tissue MD A and glutathione enzymes while reducing SOD and catalase, which may indicate the development of oxidative stress in the dynamics of tumor progression. The data obtained suggest the increase of expres- sion of oxidative stress in red blood cells and tumor tissue in CC in the dynamics of tumor progression.https://ojrs.abvpress.ru/ojrs/article/view/198cervical canceroxidative stressmalondialdehydeglutathione-reductaseglutathione-transferasesuperoxide-dismutasecatalase |
| spellingShingle | I. I. Antoneeva T. P. Gening D. R. Arslanova E. G. Sidorenko Comparative characterization of oxidative stress in cervical cancer at different clinical stages of disease Опухоли женской репродуктивной системы cervical cancer oxidative stress malondialdehyde glutathione-reductase glutathione-transferase superoxide-dismutase catalase |
| title | Comparative characterization of oxidative stress in cervical cancer at different clinical stages of disease |
| title_full | Comparative characterization of oxidative stress in cervical cancer at different clinical stages of disease |
| title_fullStr | Comparative characterization of oxidative stress in cervical cancer at different clinical stages of disease |
| title_full_unstemmed | Comparative characterization of oxidative stress in cervical cancer at different clinical stages of disease |
| title_short | Comparative characterization of oxidative stress in cervical cancer at different clinical stages of disease |
| title_sort | comparative characterization of oxidative stress in cervical cancer at different clinical stages of disease |
| topic | cervical cancer oxidative stress malondialdehyde glutathione-reductase glutathione-transferase superoxide-dismutase catalase |
| url | https://ojrs.abvpress.ru/ojrs/article/view/198 |
| work_keys_str_mv | AT iiantoneeva comparativecharacterizationofoxidativestressincervicalcanceratdifferentclinicalstagesofdisease AT tpgening comparativecharacterizationofoxidativestressincervicalcanceratdifferentclinicalstagesofdisease AT drarslanova comparativecharacterizationofoxidativestressincervicalcanceratdifferentclinicalstagesofdisease AT egsidorenko comparativecharacterizationofoxidativestressincervicalcanceratdifferentclinicalstagesofdisease |