Visual related quality of life after ICL V4c implantation in high myopia patients: a mini review

High myopia (≥ − 6.00 D) poses significant challenges to visual function and quality of life, with implantable collamer lens (ICL) V4c implantation emerging as a pivotal treatment. This mini review synthesizes evidence on visual-related quality of life (VRQoL) following ICL V4c implantation, focusin...

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Main Authors: Huailan Zhao, Siquan Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Medicine
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Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2025.1630025/full
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author Huailan Zhao
Siquan Zhu
author_facet Huailan Zhao
Siquan Zhu
author_sort Huailan Zhao
collection DOAJ
description High myopia (≥ − 6.00 D) poses significant challenges to visual function and quality of life, with implantable collamer lens (ICL) V4c implantation emerging as a pivotal treatment. This mini review synthesizes evidence on visual-related quality of life (VRQoL) following ICL V4c implantation, focusing on predictability, objective/subjective visual quality, and complications. ICL V4c demonstrates long-term safety and efficacy, with safety indices (postoperative best-corrected visual acuity/preoperative best-corrected visual acuity) of 1.01–1.10 and efficacy indices (postoperative uncorrected visual acuity/preoperative best-corrected visual acuity) exceeding 0.90 over 5 years. Objective metrics, including higher-order aberrations and intraocular scattering, remain stable or improve postoperatively, while subjective outcomes show high patient satisfaction despite common but mild issues like halos (90.1% incidence) and glare (66.7% incidence). Complications such as cataract (1.7–6.8% incidence), corneal endothelial cell loss (≤5.7% over 8 years), and ICL malposition are rare and often manageable. While axial length progression in super-high myopia requires monitoring, ICL V4c remains a robust option for enhancing VRQoL in high myopia patients. Future research should prioritize large-scale, long-term studies to validate outcomes and optimize surgical protocols.
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spelling doaj-art-3e8e6f546ced479eba6cd70d3e8188af2025-08-20T02:45:56ZengFrontiers Media S.A.Frontiers in Medicine2296-858X2025-07-011210.3389/fmed.2025.16300251630025Visual related quality of life after ICL V4c implantation in high myopia patients: a mini reviewHuailan ZhaoSiquan ZhuHigh myopia (≥ − 6.00 D) poses significant challenges to visual function and quality of life, with implantable collamer lens (ICL) V4c implantation emerging as a pivotal treatment. This mini review synthesizes evidence on visual-related quality of life (VRQoL) following ICL V4c implantation, focusing on predictability, objective/subjective visual quality, and complications. ICL V4c demonstrates long-term safety and efficacy, with safety indices (postoperative best-corrected visual acuity/preoperative best-corrected visual acuity) of 1.01–1.10 and efficacy indices (postoperative uncorrected visual acuity/preoperative best-corrected visual acuity) exceeding 0.90 over 5 years. Objective metrics, including higher-order aberrations and intraocular scattering, remain stable or improve postoperatively, while subjective outcomes show high patient satisfaction despite common but mild issues like halos (90.1% incidence) and glare (66.7% incidence). Complications such as cataract (1.7–6.8% incidence), corneal endothelial cell loss (≤5.7% over 8 years), and ICL malposition are rare and often manageable. While axial length progression in super-high myopia requires monitoring, ICL V4c remains a robust option for enhancing VRQoL in high myopia patients. Future research should prioritize large-scale, long-term studies to validate outcomes and optimize surgical protocols.https://www.frontiersin.org/articles/10.3389/fmed.2025.1630025/fullhigh myopiaICL V4cvisual-related quality of lifeobjective visual qualitysubjective visual qualitycomplications
spellingShingle Huailan Zhao
Siquan Zhu
Visual related quality of life after ICL V4c implantation in high myopia patients: a mini review
Frontiers in Medicine
high myopia
ICL V4c
visual-related quality of life
objective visual quality
subjective visual quality
complications
title Visual related quality of life after ICL V4c implantation in high myopia patients: a mini review
title_full Visual related quality of life after ICL V4c implantation in high myopia patients: a mini review
title_fullStr Visual related quality of life after ICL V4c implantation in high myopia patients: a mini review
title_full_unstemmed Visual related quality of life after ICL V4c implantation in high myopia patients: a mini review
title_short Visual related quality of life after ICL V4c implantation in high myopia patients: a mini review
title_sort visual related quality of life after icl v4c implantation in high myopia patients a mini review
topic high myopia
ICL V4c
visual-related quality of life
objective visual quality
subjective visual quality
complications
url https://www.frontiersin.org/articles/10.3389/fmed.2025.1630025/full
work_keys_str_mv AT huailanzhao visualrelatedqualityoflifeaftericlv4cimplantationinhighmyopiapatientsaminireview
AT siquanzhu visualrelatedqualityoflifeaftericlv4cimplantationinhighmyopiapatientsaminireview