Engineered endothelium-mimicking antithrombotic surfaces via combination of nitric oxide-generation with fibrinolysis strategies

Engineered endothelium-mimicking antithrombotic surfaces via combination of nitric oxide-generation with fibrinolysis strategies

Thrombosis associated with implants can severely impact therapeutic outcomes and lead to increased morbidity and mortality. Thus, developing blood-contacting materials with superior anticoagulant properties is essential to prevent and mitigate device-related thrombosis. Herein, we propose a novel si...

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Bibliographic Details
Main Authors: Wenxuan Wang, Qing Ma, Da Li, Wentai Zhang, Zhilu Yang, Wenjie Tian, Nan Huang
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-01-01
Series:Bioactive Materials
Subjects:
Nitric oxide
Fibrinolysis
Endothelium mimicking
Antithrombosis
Surface modification
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X24003980
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