Diagnosis and treatment of vascular cognitive disorders

Cognitive impairment (CI) usually is the earliest and most prevalent manifestation of cerebral vascular disease. Post stroke CI may have different clinical presentation depending on location of vascular lesion, so appropriate temporal association of CI onset with the event of stroke is of most impor...

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Main Author: V. V. Zakharov
Format: Article
Language:Russian
Published: ABV-press 2024-01-01
Series:Klinicist
Subjects:
Online Access:https://klinitsist.abvpress.ru/Klin/article/view/557
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author V. V. Zakharov
author_facet V. V. Zakharov
author_sort V. V. Zakharov
collection DOAJ
description Cognitive impairment (CI) usually is the earliest and most prevalent manifestation of cerebral vascular disease. Post stroke CI may have different clinical presentation depending on location of vascular lesion, so appropriate temporal association of CI onset with the event of stroke is of most important diagnostic value. Non-stroke (subcortical) variant of cerebral vascular disease usually is associated with small vessel disease. CI in subcortical variant is characterized with attention and executive functions deficit, frequently in combination with emotional disorders, postural instability and gait disturbances of frontal origin. Presence of vascular CI means essential need of thorough vascular risk factor (arterial hypertension, dyslipidemia, diabetes etc.) control. Vasotropic agents are prescribed with pathogenic purposes. The article presents clinical experience of nicergoline treatment of patients with vascular CI of different severity.
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spelling doaj-art-3e65c4be6c6446058d10a9e33c0c70f72025-08-20T03:45:04ZrusABV-pressKlinicist1818-83382024-01-01173122110.17650/1818-8338-2023-17-3-K694410Diagnosis and treatment of vascular cognitive disordersV. V. Zakharov0I. M. Sechenov First Moscow State Medical University of the Ministry of Health of Russia (Sechenov University)Cognitive impairment (CI) usually is the earliest and most prevalent manifestation of cerebral vascular disease. Post stroke CI may have different clinical presentation depending on location of vascular lesion, so appropriate temporal association of CI onset with the event of stroke is of most important diagnostic value. Non-stroke (subcortical) variant of cerebral vascular disease usually is associated with small vessel disease. CI in subcortical variant is characterized with attention and executive functions deficit, frequently in combination with emotional disorders, postural instability and gait disturbances of frontal origin. Presence of vascular CI means essential need of thorough vascular risk factor (arterial hypertension, dyslipidemia, diabetes etc.) control. Vasotropic agents are prescribed with pathogenic purposes. The article presents clinical experience of nicergoline treatment of patients with vascular CI of different severity.https://klinitsist.abvpress.ru/Klin/article/view/557cognitive impairmentcerebral vascular diseaserisk factorsstrokesmall vessel diseasevascular depressionfrontal dysbasianicergoline
spellingShingle V. V. Zakharov
Diagnosis and treatment of vascular cognitive disorders
Klinicist
cognitive impairment
cerebral vascular disease
risk factors
stroke
small vessel disease
vascular depression
frontal dysbasia
nicergoline
title Diagnosis and treatment of vascular cognitive disorders
title_full Diagnosis and treatment of vascular cognitive disorders
title_fullStr Diagnosis and treatment of vascular cognitive disorders
title_full_unstemmed Diagnosis and treatment of vascular cognitive disorders
title_short Diagnosis and treatment of vascular cognitive disorders
title_sort diagnosis and treatment of vascular cognitive disorders
topic cognitive impairment
cerebral vascular disease
risk factors
stroke
small vessel disease
vascular depression
frontal dysbasia
nicergoline
url https://klinitsist.abvpress.ru/Klin/article/view/557
work_keys_str_mv AT vvzakharov diagnosisandtreatmentofvascularcognitivedisorders