Long-term treatment with sulfhydryl angiotensin-converting enzyme inhibition reduces carotid intima-media thickening and improves the nitric oxide/oxidative stress pathways in newly diagnosed patients with mild to moderate primary hypertension

Long-term treatment with sulfhydryl angiotensin-converting enzyme inhibition reduces carotid intima-media thickening and improves the nitric oxide/oxidative stress pathways in newly diagnosed patients with mild to moderate primary hypertension

Aim. Sulfhydryl angiotensin-converting enzyme (ACE) inhibitors exert antiatherosclerotic effects in preclinical models and antioxidant effects in patients. However, whether ACE inhibitors have any clinically significant antiatherogenic effects remains still debated. Objectives. In mildly hypertensiv...

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Main Authors: C. Napoli, G. Bruzzese, L. J. Ignarro, E. Crimi, F. de Nigris, S. Williams-Ignarro, S. Libardi, L. Sommese, C. Fiorito, F. P. Mancini, F. Cacciatore, A. Liguori
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2012-06-01
Series:Кардиоваскулярная терапия и профилактика
Online Access:https://cardiovascular.elpub.ru/jour/article/view/1836
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