405 nm violet-blue light inactivates hepatitis C cell culture virus (HCVcc) in ex vivo human platelet concentrates and plasma

405 nm violet-blue light inactivates hepatitis C cell culture virus (HCVcc) in ex vivo human platelet concentrates and plasma

Abstract Added safety measures coupled with the development and use of pathogen reduction technologies (PRT) significantly reduces the risk of transfusion-transmitted infections (TTIs) from blood products. Current approved PRTs utilize chemical and/or UV-light based inactivation methods. While the e...

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Bibliographic Details
Main Authors: Joseph W. Jackson, Pravin R. Kaldhone, Caitlin Stewart, John Anderson, Scott MacGregor, Michelle Maclean, Marian Major, Chintamani D. Atreya
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
Pathogen inactivation
HCV
Platelets
Plasma
blue light
405 nm light
Online Access:https://doi.org/10.1038/s41598-024-83171-3
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