Synthetic Peptides as Structural Maquettes of Angiotensin-I Converting Enzyme Catalytic Sites

The rational design of synthetic peptides is proposed as an efficient strategy for the structural investigation of crucial protein domains difficult to be produced. Only after half a century since the function of ACE was first reported, was its crystal structure solved. The main obstacle to be overc...

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Bibliographic Details
Main Authors: Zinovia Spyranti, Athanassios S. Galanis, George Pairas, Georgios A. Spyroulias, Evy Manessi-Zoupa, Paul Cordopatis
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Bioinorganic Chemistry and Applications
Online Access:http://dx.doi.org/10.1155/2010/820476
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