XRD, EDX and FTIR study of the bioactivity of 60S GLASS doped with La and Y under <em>in vitro</em> conditions
The aim of the work is the synthesis and study of the bioactivity of sol-gel glass (BG 60S) with molar composition 60 % SiO2, 36 % CaO, 4 % P2O5 and samples doped with La and Y in vitro; studying their structural properties and changes upon contact with a model physiological environment (Kokubo’s S...
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Chuiko Institute of Surface Chemistry of NAS of Ukraine
2023-02-01
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| Series: | Хімія, фізика та технологія поверхні |
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| Online Access: | https://cpts.com.ua/index.php/cpts/article/view/663 |
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| author | A. P. Kusyak O. I. Oranska D. Marcin Behunova A. I. Petranovska V. S. Chornyi O. A. Bur'yanov V. A. Dubok P. P. Gorbyk |
| author_facet | A. P. Kusyak O. I. Oranska D. Marcin Behunova A. I. Petranovska V. S. Chornyi O. A. Bur'yanov V. A. Dubok P. P. Gorbyk |
| author_sort | A. P. Kusyak |
| collection | DOAJ |
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The aim of the work is the synthesis and study of the bioactivity of sol-gel glass (BG 60S) with molar composition 60 % SiO2, 36 % CaO, 4 % P2O5 and samples doped with La and Y in vitro; studying their structural properties and changes upon contact with a model physiological environment (Kokubo’s SBF), as well as justifying the possibility of their use for tissue regeneration and tissue engineering.
According to the results of research, the interaction of synthesized samples with SBF leads to a change in the phase composition and the ratio of amorphous and crystalline components. It is necessary to note long and intensive processes involving CO32– ions for unalloyed and alloyed samples. The appearance of calcium carbonate in the form of vaterite with a simultaneous increase in the calcite content is one of the signs of high bioactivity of the synthesized samples. According to the results of XRD, EDX and FTIR studies after 28 days of soaking in SBF, the predominant surface elements are Ca and P in the composition of hydroxyapatite, and the elemental composition indicates active ion exchange processes according to the theory of bioactive glass dissolution in physiological fluids.
The change in the ratio of crystalline phases with the inclusion of mainly one crystalline phase of hydroxopatite within 28 days leads to a better structuredness of the surface of the synthesized samples and indicates that they have osteoconductive properties, can connect with bone tissue and have the appropriate biodegradation ability.
The results of the study indicate the promising nature of synthesized materials for tissue regeneration and tissue engineering.
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| format | Article |
| id | doaj-art-3e48589bf53e4a7086d92f0356c2b072 |
| institution | Kabale University |
| issn | 2079-1704 2518-1238 |
| language | English |
| publishDate | 2023-02-01 |
| publisher | Chuiko Institute of Surface Chemistry of NAS of Ukraine |
| record_format | Article |
| series | Хімія, фізика та технологія поверхні |
| spelling | doaj-art-3e48589bf53e4a7086d92f0356c2b0722025-08-20T03:31:10ZengChuiko Institute of Surface Chemistry of NAS of UkraineХімія, фізика та технологія поверхні2079-17042518-12382023-02-0114110.15407/hftp14.01.093XRD, EDX and FTIR study of the bioactivity of 60S GLASS doped with La and Y under <em>in vitro</em> conditionsA. P. Kusyak0O. I. Oranska1D. Marcin Behunova2A. I. Petranovska3V. S. Chornyi4O. A. Bur'yanov5V. A. Dubok6P. P. Gorbyk7Chuiko Institute of Surface Chemistry of National Academy of Sciences of UkraineChuiko Institute of Surface Chemistry of National Academy of Sciences of UkraineInstitute of Geotechnics of Slovak Academy of SciencesChuiko Institute of Surface Chemistry of National Academy of Sciences of UkraineBogomolets National Medical UniversityBogomolets National Medical UniversityFrantsevich Institute of Problems of Materials Science of National Academy of Sciences of UkraineChuiko Institute of Surface Chemistry of National Academy of Sciences of Ukraine The aim of the work is the synthesis and study of the bioactivity of sol-gel glass (BG 60S) with molar composition 60 % SiO2, 36 % CaO, 4 % P2O5 and samples doped with La and Y in vitro; studying their structural properties and changes upon contact with a model physiological environment (Kokubo’s SBF), as well as justifying the possibility of their use for tissue regeneration and tissue engineering. According to the results of research, the interaction of synthesized samples with SBF leads to a change in the phase composition and the ratio of amorphous and crystalline components. It is necessary to note long and intensive processes involving CO32– ions for unalloyed and alloyed samples. The appearance of calcium carbonate in the form of vaterite with a simultaneous increase in the calcite content is one of the signs of high bioactivity of the synthesized samples. According to the results of XRD, EDX and FTIR studies after 28 days of soaking in SBF, the predominant surface elements are Ca and P in the composition of hydroxyapatite, and the elemental composition indicates active ion exchange processes according to the theory of bioactive glass dissolution in physiological fluids. The change in the ratio of crystalline phases with the inclusion of mainly one crystalline phase of hydroxopatite within 28 days leads to a better structuredness of the surface of the synthesized samples and indicates that they have osteoconductive properties, can connect with bone tissue and have the appropriate biodegradation ability. The results of the study indicate the promising nature of synthesized materials for tissue regeneration and tissue engineering. https://cpts.com.ua/index.php/cpts/article/view/663bioactive sol-gel glassosteoconductivitytissue regenerationtissue engineering |
| spellingShingle | A. P. Kusyak O. I. Oranska D. Marcin Behunova A. I. Petranovska V. S. Chornyi O. A. Bur'yanov V. A. Dubok P. P. Gorbyk XRD, EDX and FTIR study of the bioactivity of 60S GLASS doped with La and Y under <em>in vitro</em> conditions Хімія, фізика та технологія поверхні bioactive sol-gel glass osteoconductivity tissue regeneration tissue engineering |
| title | XRD, EDX and FTIR study of the bioactivity of 60S GLASS doped with La and Y under <em>in vitro</em> conditions |
| title_full | XRD, EDX and FTIR study of the bioactivity of 60S GLASS doped with La and Y under <em>in vitro</em> conditions |
| title_fullStr | XRD, EDX and FTIR study of the bioactivity of 60S GLASS doped with La and Y under <em>in vitro</em> conditions |
| title_full_unstemmed | XRD, EDX and FTIR study of the bioactivity of 60S GLASS doped with La and Y under <em>in vitro</em> conditions |
| title_short | XRD, EDX and FTIR study of the bioactivity of 60S GLASS doped with La and Y under <em>in vitro</em> conditions |
| title_sort | xrd edx and ftir study of the bioactivity of 60s glass doped with la and y under em in vitro em conditions |
| topic | bioactive sol-gel glass osteoconductivity tissue regeneration tissue engineering |
| url | https://cpts.com.ua/index.php/cpts/article/view/663 |
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