Maternal PRDM10 activates essential genes for oocyte-to-embryo transition

Maternal PRDM10 activates essential genes for oocyte-to-embryo transition

Abstract PR/SET domain-containing (PRDM) proteins are metazoan-specific transcriptional regulators that play diverse roles in mammalian development and disease. Several members such as PRDM1, PRDM14 and PRDM9, have been implicated in germ cell specification and homoeostasis and are essential to fert...

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Main Authors: Michelle K. Y. Seah, Brenda Y. Han, Yan Huang, Louise J. H. Rasmussen, Andrina J. Stäubli, Judith Bello-Rodríguez, Andrew Chi-Ho Chan, Maxime Gasnier, Heike Wollmann, Ernesto Guccione, Daniel M. Messerschmidt
Format: Article
Language:English
Published: Nature Portfolio 2025-02-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-025-56991-8
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