Angiogenesis-related genes and immune microenvironment in moyamoya disease: a transcriptomic and functional analysis

Angiogenesis-related genes and immune microenvironment in moyamoya disease: a transcriptomic and functional analysis

Abstract Background Moyamoya disease (MMD) is a chronic, progressive occlusive cerebrovascular disease. It causes recurrent cerebrovascular stroke due to vascular closure and proliferation. An unclear pathophysiological mechanism is the most significant obstacle in the diagnosis and treatment of MMD...

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Main Authors: Zhenyu Zhou, Hongchuan Niu, Shaoqi Xu, Junze Zhang, Yutong Liu, Chengxu Lei, Shihao He, Yuanli Zhao
Format: Article
Language:English
Published: BMC 2025-07-01
Series:Orphanet Journal of Rare Diseases
Subjects:
Moyamoya disease
Angiogenesis
Immune
Multi-omics
Online Access:https://doi.org/10.1186/s13023-025-03945-4
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