Immunoinformatic-Based Mapping of Cytotoxic T-Cell Epitopes of Overexpressed Proteins in Four High-mortality Cancers Determined Through Gene Expression Analysis

Immunoinformatic-Based Mapping of Cytotoxic T-Cell Epitopes of Overexpressed Proteins in Four High-mortality Cancers Determined Through Gene Expression Analysis

Background: Pancreatic, liver, colorectal, and lung cancer are some of the cancers with the highest mortality rates and the poorest prognosis. The discovery of cytotoxic T-cell (CD8+) epitopes in tumor-associated antigens (TAAs) common to these four types of cancer could lead to the development of p...

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Bibliographic Details
Main Authors: Gaitano Arturo Lano III, Leana Rich Herrera-Ong
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Biomedical and Biotechnology Research Journal
Subjects:
cancer vaccines
cancer
gene expression analysis
immunoinformatics
t-cell epitope
Online Access:https://journals.lww.com/10.4103/bbrj.bbrj_271_24
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