Amphiphiles Self-Assembly: Basic Concepts and Future Perspectives of Supramolecular Approaches

Amphiphiles are synthetic or natural molecules with the ability to self-assemble into a wide variety of structures including micelles, vesicles, nanotubes, nanofibers, and lamellae. Self-assembly processes of amphiphiles have been widely used to mimic biological systems, such as assembly of lipids a...

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Main Authors: Domenico Lombardo, Mikhail A. Kiselev, Salvatore Magazù, Pietro Calandra
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Advances in Condensed Matter Physics
Online Access:http://dx.doi.org/10.1155/2015/151683
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author Domenico Lombardo
Mikhail A. Kiselev
Salvatore Magazù
Pietro Calandra
author_facet Domenico Lombardo
Mikhail A. Kiselev
Salvatore Magazù
Pietro Calandra
author_sort Domenico Lombardo
collection DOAJ
description Amphiphiles are synthetic or natural molecules with the ability to self-assemble into a wide variety of structures including micelles, vesicles, nanotubes, nanofibers, and lamellae. Self-assembly processes of amphiphiles have been widely used to mimic biological systems, such as assembly of lipids and proteins, while their integrated actions allow the performance of highly specific cellular functions which has paved a way for bottom-up bionanotechnology. While amphiphiles self-assembly has attracted considerable attention for decades due to their extensive applications in material science, drug and gene delivery, recent developments in nanoscience stimulated the combination of the simple approaches of amphiphile assembly with the advanced concept of supramolecular self-assembly for the development of more complex, hierarchical nanostructures. Introduction of stimulus responsive supramolecular amphiphile assembly-disassembly processes provides particularly novel approaches for impacting bionanotechnology applications. Leading examples of these novel self-assembly processes can be found, in fact, in biosystems where assemblies of different amphiphilic macrocomponents and their integrated actions allow the performance of highly specific biological functions. In this perspective, we summarize in this tutorial review the basic concept and recent research on self-assembly of traditional amphiphilic molecules (such as surfactants, amphiphile-like polymers, or lipids) and more recent concepts of supramolecular amphiphiles assembly which have become increasingly important in emerging nanotechnology.
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spelling doaj-art-3e2ebf78cc2a44f5b64f7fd01d8504e42025-02-03T01:31:10ZengWileyAdvances in Condensed Matter Physics1687-81081687-81242015-01-01201510.1155/2015/151683151683Amphiphiles Self-Assembly: Basic Concepts and Future Perspectives of Supramolecular ApproachesDomenico Lombardo0Mikhail A. Kiselev1Salvatore Magazù2Pietro Calandra3Consiglio Nazionale delle Ricerche (CNR), Istituto per i Processi Chimico-Fisici (IPCF), Viale F.S. D’Alcontres, No. 37, 98158 Messina, ItalyFrank Laboratory of Neutron Physics, Joint Institute for Nuclear Research, Ulica Joliot-Curie 6, Dubna, Moscow 141980, RussiaDipartimento di Fisica e Scienze della Terra, Università di Messina, Viale F.S. D’Alcontres, No. 31, 98158 Messina, ItalyConsiglio Nazionale delle Ricerche (CNR), Istituto per lo Studio dei Materiali Nanostrutturati (ISMN), Via Salaria km 29.300, Monterotondo Stazione, 00015 Roma, ItalyAmphiphiles are synthetic or natural molecules with the ability to self-assemble into a wide variety of structures including micelles, vesicles, nanotubes, nanofibers, and lamellae. Self-assembly processes of amphiphiles have been widely used to mimic biological systems, such as assembly of lipids and proteins, while their integrated actions allow the performance of highly specific cellular functions which has paved a way for bottom-up bionanotechnology. While amphiphiles self-assembly has attracted considerable attention for decades due to their extensive applications in material science, drug and gene delivery, recent developments in nanoscience stimulated the combination of the simple approaches of amphiphile assembly with the advanced concept of supramolecular self-assembly for the development of more complex, hierarchical nanostructures. Introduction of stimulus responsive supramolecular amphiphile assembly-disassembly processes provides particularly novel approaches for impacting bionanotechnology applications. Leading examples of these novel self-assembly processes can be found, in fact, in biosystems where assemblies of different amphiphilic macrocomponents and their integrated actions allow the performance of highly specific biological functions. In this perspective, we summarize in this tutorial review the basic concept and recent research on self-assembly of traditional amphiphilic molecules (such as surfactants, amphiphile-like polymers, or lipids) and more recent concepts of supramolecular amphiphiles assembly which have become increasingly important in emerging nanotechnology.http://dx.doi.org/10.1155/2015/151683
spellingShingle Domenico Lombardo
Mikhail A. Kiselev
Salvatore Magazù
Pietro Calandra
Amphiphiles Self-Assembly: Basic Concepts and Future Perspectives of Supramolecular Approaches
Advances in Condensed Matter Physics
title Amphiphiles Self-Assembly: Basic Concepts and Future Perspectives of Supramolecular Approaches
title_full Amphiphiles Self-Assembly: Basic Concepts and Future Perspectives of Supramolecular Approaches
title_fullStr Amphiphiles Self-Assembly: Basic Concepts and Future Perspectives of Supramolecular Approaches
title_full_unstemmed Amphiphiles Self-Assembly: Basic Concepts and Future Perspectives of Supramolecular Approaches
title_short Amphiphiles Self-Assembly: Basic Concepts and Future Perspectives of Supramolecular Approaches
title_sort amphiphiles self assembly basic concepts and future perspectives of supramolecular approaches
url http://dx.doi.org/10.1155/2015/151683
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