Probiotic significance of Lactobacillus strains: a comprehensive review on health impacts, research gaps, and future prospects

A rising corpus of research has shown the beneficial effects of probiotic Lactobacilli on human health, contributing to the growing popularity of these microorganisms in recent decades. The gastrointestinal and urinary tracts are home to these bacteria, which play a vital role in the microbial flora...

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Main Authors: Abdul Bari Shah, Aizhamal Baiseitova, Muhammad Zahoor, Ishaq Ahmad, Muhammad Ikram, Allah Bakhsh, Murad Ali Shah, Imdad Ali, Muhammad Idress, Riaz Ullah, Fahd A. Nasr, Mohammed Al-Zharani
Format: Article
Language:English
Published: Taylor & Francis Group 2024-12-01
Series:Gut Microbes
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Online Access:https://www.tandfonline.com/doi/10.1080/19490976.2024.2431643
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author Abdul Bari Shah
Aizhamal Baiseitova
Muhammad Zahoor
Ishaq Ahmad
Muhammad Ikram
Allah Bakhsh
Murad Ali Shah
Imdad Ali
Muhammad Idress
Riaz Ullah
Fahd A. Nasr
Mohammed Al-Zharani
author_facet Abdul Bari Shah
Aizhamal Baiseitova
Muhammad Zahoor
Ishaq Ahmad
Muhammad Ikram
Allah Bakhsh
Murad Ali Shah
Imdad Ali
Muhammad Idress
Riaz Ullah
Fahd A. Nasr
Mohammed Al-Zharani
author_sort Abdul Bari Shah
collection DOAJ
description A rising corpus of research has shown the beneficial effects of probiotic Lactobacilli on human health, contributing to the growing popularity of these microorganisms in recent decades. The gastrointestinal and urinary tracts are home to these bacteria, which play a vital role in the microbial flora of both humans and animals. The Lactobacillus probiotic, i.e, Lactobacillus plantarum, Lactobacillus paracasei, Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus rhamnosus, Lactobacillus crispatus, Lactobacillus gasseri, Lactobacillus reuteri, and Lactobacillus bulgaricus, are highly recognized for their remarkable probiotic qualities. The current study aims to highlight the beneficial effects of probiotics in different health conditions, point out the research gap, and highlight the future directives for the safe use of these probiotics in several health issues. Most importantly, we have added the most recent literature related to the characteristics and usage of these probiotics in clinical and pre-clinical settings. Based on the above statement, we believe that this is the first report on the application of probiotics in human diseases. By providing a deeper knowledge of the complex functions these probiotics play in both human and animal health, our analysis will direct future studies and developments in this rapidly developing field.
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spelling doaj-art-3e2de076f4f847d98175ebb99c6439e62025-08-20T02:23:31ZengTaylor & Francis GroupGut Microbes1949-09761949-09842024-12-0116110.1080/19490976.2024.2431643Probiotic significance of Lactobacillus strains: a comprehensive review on health impacts, research gaps, and future prospectsAbdul Bari Shah0Aizhamal Baiseitova1Muhammad Zahoor2Ishaq Ahmad3Muhammad Ikram4Allah Bakhsh5Murad Ali Shah6Imdad Ali7Muhammad Idress8Riaz Ullah9Fahd A. Nasr10Mohammed Al-Zharani11Natural Products Research Institute, College of Pharmacy, Seoul National University, Seoul, Republic of KoreaDivision of Applied Life Science (BK21 Four), IALS, Gyeongsang National University, Jinju, Republic of KoreaDepartment of Biochemistry, University of Malakand, Chakdara, PakistanDepartment of Marine Environmental Engineering, Gyeongsang National University, Gyeongsangnam-do, Republic of KoreaInstitute of Pharmaceutical Sciences, Khyber Medical University, Peshawar, Hayatabad, PakistanAtta-ur-Rahman School of Applied Biosciences (ASAB), National University of Sciences and Technology (NUST), Islamabad, PakistanConvergence Research Center for Brain Science, Brain Science Institute, Korea Institute of Science and Technology (KIST), Seoul, Republic of KoreaCentre for Research in Agricultural Genomics (CRAG), CSIC-IRTA-UAB-UB, Campus UAB, Barcelona, Bellaterra, SpainDivision of Applied Life Science (BK21 Four), IALS, Gyeongsang National University, Jinju, Republic of KoreaDepartment of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi ArabiaBiology Department, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi ArabiaBiology Department, College of Science, Imam Mohammad Ibn Saud Islamic University (IMSIU), Riyadh, Saudi ArabiaA rising corpus of research has shown the beneficial effects of probiotic Lactobacilli on human health, contributing to the growing popularity of these microorganisms in recent decades. The gastrointestinal and urinary tracts are home to these bacteria, which play a vital role in the microbial flora of both humans and animals. The Lactobacillus probiotic, i.e, Lactobacillus plantarum, Lactobacillus paracasei, Lactobacillus acidophilus, Lactobacillus casei, Lactobacillus rhamnosus, Lactobacillus crispatus, Lactobacillus gasseri, Lactobacillus reuteri, and Lactobacillus bulgaricus, are highly recognized for their remarkable probiotic qualities. The current study aims to highlight the beneficial effects of probiotics in different health conditions, point out the research gap, and highlight the future directives for the safe use of these probiotics in several health issues. Most importantly, we have added the most recent literature related to the characteristics and usage of these probiotics in clinical and pre-clinical settings. Based on the above statement, we believe that this is the first report on the application of probiotics in human diseases. By providing a deeper knowledge of the complex functions these probiotics play in both human and animal health, our analysis will direct future studies and developments in this rapidly developing field.https://www.tandfonline.com/doi/10.1080/19490976.2024.2431643Lactobacillusprobioticgastrointestinal tracthuman health
spellingShingle Abdul Bari Shah
Aizhamal Baiseitova
Muhammad Zahoor
Ishaq Ahmad
Muhammad Ikram
Allah Bakhsh
Murad Ali Shah
Imdad Ali
Muhammad Idress
Riaz Ullah
Fahd A. Nasr
Mohammed Al-Zharani
Probiotic significance of Lactobacillus strains: a comprehensive review on health impacts, research gaps, and future prospects
Gut Microbes
Lactobacillus
probiotic
gastrointestinal tract
human health
title Probiotic significance of Lactobacillus strains: a comprehensive review on health impacts, research gaps, and future prospects
title_full Probiotic significance of Lactobacillus strains: a comprehensive review on health impacts, research gaps, and future prospects
title_fullStr Probiotic significance of Lactobacillus strains: a comprehensive review on health impacts, research gaps, and future prospects
title_full_unstemmed Probiotic significance of Lactobacillus strains: a comprehensive review on health impacts, research gaps, and future prospects
title_short Probiotic significance of Lactobacillus strains: a comprehensive review on health impacts, research gaps, and future prospects
title_sort probiotic significance of lactobacillus strains a comprehensive review on health impacts research gaps and future prospects
topic Lactobacillus
probiotic
gastrointestinal tract
human health
url https://www.tandfonline.com/doi/10.1080/19490976.2024.2431643
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