A rare case of bladder paraganglioma treated successfully with robotic partial cystectomy

Bladder paragangliomas are rare extra-adrenal urological tumors that account for around 0.05% of bladder cancers. Their diagnosis is often delayed because of the rarity of these tumors. There is a risk of an intraoperative hypertensive crisis if not diagnosed or identified before surgical removal. W...

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Main Authors: Kalyan M Shekhda, Jessal M Palan, Christo B Albor, Simon Wan, Teng-Teng Chung
Format: Article
Language:English
Published: Bioscientifica 2025-01-01
Series:Endocrine Oncology
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Online Access:https://eo.bioscientifica.com/view/journals/eo/5/1/EO-24-0044.xml
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author Kalyan M Shekhda
Jessal M Palan
Christo B Albor
Simon Wan
Teng-Teng Chung
author_facet Kalyan M Shekhda
Jessal M Palan
Christo B Albor
Simon Wan
Teng-Teng Chung
author_sort Kalyan M Shekhda
collection DOAJ
description Bladder paragangliomas are rare extra-adrenal urological tumors that account for around 0.05% of bladder cancers. Their diagnosis is often delayed because of the rarity of these tumors. There is a risk of an intraoperative hypertensive crisis if not diagnosed or identified before surgical removal. We describe a case of a 36-year-old lady presented with a 10-year history of post-micturition palpitations and headaches. Her biochemical workup showed raised urinary normetanephrine levels and imaging showed a 123I MIBG-avid bladder mass compatible with bladder paraganglioma, although interestingly almost no tracer was picked up in 68Ga DOTATATE imaging. She was started on phenoxybenzamine to control her blood pressure prior to surgery. She underwent a successful robotic partial cystectomy with no complications. After surgery, she remained symptom-free. Bladder paragangliomas are rare neuroendocrine tumors of the bladder, which need to be diagnosed and managed effectively to avoid intraoperative and long-term complications.
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institution Kabale University
issn 2634-4793
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publishDate 2025-01-01
publisher Bioscientifica
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series Endocrine Oncology
spelling doaj-art-3e27ce6381be4baabc2d1da21dded7a32025-01-07T17:18:01ZengBioscientificaEndocrine Oncology2634-47932025-01-015110.1530/EO-24-00441A rare case of bladder paraganglioma treated successfully with robotic partial cystectomyKalyan M Shekhda0Jessal M Palan1Christo B Albor2Simon Wan3Teng-Teng Chung4Department of Diabetes and Endocrinology, University College London Hospital NHS Foundation Trust, London, UKDepartment of Diabetes and Endocrinology, Whittington Hospital NHS Foundation Trust, London, UKDepartment of Diabetes and Endocrinology, Kings College Hospital NHS Foundation Trust, London, UKDepartment of Radiology and Nuclear Medicine, University College London Hospital NHS Foundation Trust, London, UKDepartment of Diabetes and Endocrinology, University College London Hospital NHS Foundation Trust, London, UKBladder paragangliomas are rare extra-adrenal urological tumors that account for around 0.05% of bladder cancers. Their diagnosis is often delayed because of the rarity of these tumors. There is a risk of an intraoperative hypertensive crisis if not diagnosed or identified before surgical removal. We describe a case of a 36-year-old lady presented with a 10-year history of post-micturition palpitations and headaches. Her biochemical workup showed raised urinary normetanephrine levels and imaging showed a 123I MIBG-avid bladder mass compatible with bladder paraganglioma, although interestingly almost no tracer was picked up in 68Ga DOTATATE imaging. She was started on phenoxybenzamine to control her blood pressure prior to surgery. She underwent a successful robotic partial cystectomy with no complications. After surgery, she remained symptom-free. Bladder paragangliomas are rare neuroendocrine tumors of the bladder, which need to be diagnosed and managed effectively to avoid intraoperative and long-term complications.https://eo.bioscientifica.com/view/journals/eo/5/1/EO-24-0044.xmlbladder paragangliomapartial cystectomyga-dotatate scanrobotic partial cystectomy
spellingShingle Kalyan M Shekhda
Jessal M Palan
Christo B Albor
Simon Wan
Teng-Teng Chung
A rare case of bladder paraganglioma treated successfully with robotic partial cystectomy
Endocrine Oncology
bladder paraganglioma
partial cystectomy
ga-dotatate scan
robotic partial cystectomy
title A rare case of bladder paraganglioma treated successfully with robotic partial cystectomy
title_full A rare case of bladder paraganglioma treated successfully with robotic partial cystectomy
title_fullStr A rare case of bladder paraganglioma treated successfully with robotic partial cystectomy
title_full_unstemmed A rare case of bladder paraganglioma treated successfully with robotic partial cystectomy
title_short A rare case of bladder paraganglioma treated successfully with robotic partial cystectomy
title_sort rare case of bladder paraganglioma treated successfully with robotic partial cystectomy
topic bladder paraganglioma
partial cystectomy
ga-dotatate scan
robotic partial cystectomy
url https://eo.bioscientifica.com/view/journals/eo/5/1/EO-24-0044.xml
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