Investigating the relationship between sleep disturbances and cortical thickness, brainstem volume, amyloid accumulation, and inflammatory markers in Parkinson's disease patients

Investigating the relationship between sleep disturbances and cortical thickness, brainstem volume, amyloid accumulation, and inflammatory markers in Parkinson's disease patients

Background: This study aimed to explore the relationship between self-reported sleep disturbances (e.g., insomnia, REM sleep behavior disorder [RBD]) and cortical thickness, brainstem volume, amyloid accumulation, and inflammatory markers in Parkinson's disease (PD) patients. Methods: We conduc...

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Bibliographic Details
Main Authors: Min Chen, Gongbing Guo, Shuangyu Liu, Jingjing Cai, Xueying Tong, Xia Liu, Yufei Zhang, Yanhong Chen, Jiangtao Huo
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Experimental Gerontology
Subjects:
Parkinson's disease
Sleep disturbances
Cortical thickness
Brainstem volume
Amyloid-beta
Inflammation
Online Access:http://www.sciencedirect.com/science/article/pii/S0531556525000919
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