Genetic and metabolic factors influencing skin yellowness in yellow-feathered broilers

The degree of yellowness of the skin is an important factor affecting the market popularity and sales price of yellow-feathered broilers. Despite its commercial importance, the specific pigments and genetic mechanisms involved remain unclear. This study identified lutein as the primary carotenoid in...

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Main Authors: Rongqin Huang, Xianqi Deng, Jingwen Wu, Wen Luo
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Poultry Science
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Online Access:http://www.sciencedirect.com/science/article/pii/S003257912401112X
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author Rongqin Huang
Xianqi Deng
Jingwen Wu
Wen Luo
author_facet Rongqin Huang
Xianqi Deng
Jingwen Wu
Wen Luo
author_sort Rongqin Huang
collection DOAJ
description The degree of yellowness of the skin is an important factor affecting the market popularity and sales price of yellow-feathered broilers. Despite its commercial importance, the specific pigments and genetic mechanisms involved remain unclear. This study identified lutein as the primary carotenoid in the skin and established serum lutein concentration as a molecular marker for predicting skin yellowness in carcasses. Through RNA sequencing of broilers with varying yellowness, we identified key genes like CYP26A1, CYP1B1, CYP2C18, CYP2W1, HSD17B2, AOX1, KMO, PLIN1, and RET, which may regulate carotenoid absorption and deposition. Additionally, a single nucleotide polymorphism in the CYP1A1 gene was significantly associated with skin yellowness in Ma-Huang chickens. Overall, this study examined the primary pigment types that influence the skin yellowness of yellow-feathered broilers, emphasizing that lutein can serve as a molecular marker for skin yellowness and providing insights into the regulatory factors that regulate skin yellowness. These findings provide essential theoretical support for the breeding of skin color traits in yellow-feathered broilers.
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spelling doaj-art-3e21ccf51316433297abc93ade63f22f2025-01-22T05:40:23ZengElsevierPoultry Science0032-57912025-01-011041104534Genetic and metabolic factors influencing skin yellowness in yellow-feathered broilersRongqin Huang0Xianqi Deng1Jingwen Wu2Wen Luo3Department of Animal Genetics, Breeding and Reproduction, College of Animal Science, South China Agricultural University, Guangzhou 510642, China; Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, and Key Lab of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture and Rural Affair, South China Agricultural University, Guangzhou 510642, ChinaDepartment of Animal Genetics, Breeding and Reproduction, College of Animal Science, South China Agricultural University, Guangzhou 510642, China; Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, and Key Lab of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture and Rural Affair, South China Agricultural University, Guangzhou 510642, ChinaDepartment of Animal Genetics, Breeding and Reproduction, College of Animal Science, South China Agricultural University, Guangzhou 510642, China; Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, and Key Lab of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture and Rural Affair, South China Agricultural University, Guangzhou 510642, ChinaState Key Laboratory of Livestock and Poultry Breeding, and Lingnan Guangdong Laboratory of Agriculture, South China Agricultural University, Guangzhou 510642, China; Department of Animal Genetics, Breeding and Reproduction, College of Animal Science, South China Agricultural University, Guangzhou 510642, China; Guangdong Provincial Key Lab of Agro-Animal Genomics and Molecular Breeding, and Key Lab of Chicken Genetics, Breeding and Reproduction, Ministry of Agriculture and Rural Affair, South China Agricultural University, Guangzhou 510642, China; Corresponding author at: College of Animal Science, South China Agricultural University, Guangzhou 510642, Guangdong Province, China.The degree of yellowness of the skin is an important factor affecting the market popularity and sales price of yellow-feathered broilers. Despite its commercial importance, the specific pigments and genetic mechanisms involved remain unclear. This study identified lutein as the primary carotenoid in the skin and established serum lutein concentration as a molecular marker for predicting skin yellowness in carcasses. Through RNA sequencing of broilers with varying yellowness, we identified key genes like CYP26A1, CYP1B1, CYP2C18, CYP2W1, HSD17B2, AOX1, KMO, PLIN1, and RET, which may regulate carotenoid absorption and deposition. Additionally, a single nucleotide polymorphism in the CYP1A1 gene was significantly associated with skin yellowness in Ma-Huang chickens. Overall, this study examined the primary pigment types that influence the skin yellowness of yellow-feathered broilers, emphasizing that lutein can serve as a molecular marker for skin yellowness and providing insights into the regulatory factors that regulate skin yellowness. These findings provide essential theoretical support for the breeding of skin color traits in yellow-feathered broilers.http://www.sciencedirect.com/science/article/pii/S003257912401112XYellow-feathered broilersSkin yellownessLuteinmolecular markersCYP1A1
spellingShingle Rongqin Huang
Xianqi Deng
Jingwen Wu
Wen Luo
Genetic and metabolic factors influencing skin yellowness in yellow-feathered broilers
Poultry Science
Yellow-feathered broilers
Skin yellowness
Lutein
molecular markers
CYP1A1
title Genetic and metabolic factors influencing skin yellowness in yellow-feathered broilers
title_full Genetic and metabolic factors influencing skin yellowness in yellow-feathered broilers
title_fullStr Genetic and metabolic factors influencing skin yellowness in yellow-feathered broilers
title_full_unstemmed Genetic and metabolic factors influencing skin yellowness in yellow-feathered broilers
title_short Genetic and metabolic factors influencing skin yellowness in yellow-feathered broilers
title_sort genetic and metabolic factors influencing skin yellowness in yellow feathered broilers
topic Yellow-feathered broilers
Skin yellowness
Lutein
molecular markers
CYP1A1
url http://www.sciencedirect.com/science/article/pii/S003257912401112X
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AT xianqideng geneticandmetabolicfactorsinfluencingskinyellownessinyellowfeatheredbroilers
AT jingwenwu geneticandmetabolicfactorsinfluencingskinyellownessinyellowfeatheredbroilers
AT wenluo geneticandmetabolicfactorsinfluencingskinyellownessinyellowfeatheredbroilers