Aging-dependent change in Th17 and cytokine response in multiple sclerosis

Aging-dependent change in Th17 and cytokine response in multiple sclerosis

Abstract Background Multiple sclerosis (MS) is a chronic autoimmune disease damaging the central nervous system. Diminished inflammatory disease activity (DA) as people with MS (pwMS) age motivated randomized clinical trials assessing disease-modifying therapy (DMT) discontinuation in older pwMS giv...

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Bibliographic Details
Main Authors: Wen Zhu, Shankar Revu, Chenyi Chen, Megan Dahl, Archana Ramkumar, Conor Kelly, Mandy J. McGeachy, Zongqi Xia
Format: Article
Language:English
Published: BMC 2025-06-01
Series:Journal of Neuroinflammation
Subjects:
Multiple sclerosis
Myelin basic protein
Th17
Aging
Relapse
Inflammatory disease activity
Online Access:https://doi.org/10.1186/s12974-025-03474-8
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