Thrombotic Thrombocytopenic Purpura Associated with Pneumococcal Sepsis
The first documented case of thrombotic thrombocytopenic purpura (TTP) associated with pneumococcal septicemia is reported. This association has been previously demonstrated with hemolytic uremic syndrome. The patient presented with recurrent seizures, oliguric renal failure, fever, thrombocytopenia...
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| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Wiley
1993-01-01
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| Series: | Canadian Journal of Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/1993/921521 |
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| _version_ | 1832555525269618688 |
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| author | Jeffrey R Schriber John J Freedman Joseph M Brandwein |
| author_facet | Jeffrey R Schriber John J Freedman Joseph M Brandwein |
| author_sort | Jeffrey R Schriber |
| collection | DOAJ |
| description | The first documented case of thrombotic thrombocytopenic purpura (TTP) associated with pneumococcal septicemia is reported. This association has been previously demonstrated with hemolytic uremic syndrome. The patient presented with recurrent seizures, oliguric renal failure, fever, thrombocytopenia and microangiopathic hemolytic anemia; coagulation studies were normal. Blood and sputum cultures were positive for Streptococcus pneumoniae. The patient responded to therapy with plasmapheresis and antiplatelet agents as well as antibiotics. Coincident infection should be searched for in all cases of TTP. |
| format | Article |
| id | doaj-art-3e12bf03aedd4c3da219fc56303e2078 |
| institution | Kabale University |
| issn | 1180-2332 |
| language | English |
| publishDate | 1993-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Canadian Journal of Infectious Diseases |
| spelling | doaj-art-3e12bf03aedd4c3da219fc56303e20782025-02-03T05:47:56ZengWileyCanadian Journal of Infectious Diseases1180-23321993-01-014314514710.1155/1993/921521Thrombotic Thrombocytopenic Purpura Associated with Pneumococcal SepsisJeffrey R Schriber0John J Freedman1Joseph M Brandwein2Division of Hematology, St Michael’s Hospital, and, University of Toronto, Toronto, Ontario, CanadaDivision of Hematology, St Michael’s Hospital, and, University of Toronto, Toronto, Ontario, CanadaDivision of Hematology, St Michael’s Hospital, and, University of Toronto, Toronto, Ontario, CanadaThe first documented case of thrombotic thrombocytopenic purpura (TTP) associated with pneumococcal septicemia is reported. This association has been previously demonstrated with hemolytic uremic syndrome. The patient presented with recurrent seizures, oliguric renal failure, fever, thrombocytopenia and microangiopathic hemolytic anemia; coagulation studies were normal. Blood and sputum cultures were positive for Streptococcus pneumoniae. The patient responded to therapy with plasmapheresis and antiplatelet agents as well as antibiotics. Coincident infection should be searched for in all cases of TTP.http://dx.doi.org/10.1155/1993/921521 |
| spellingShingle | Jeffrey R Schriber John J Freedman Joseph M Brandwein Thrombotic Thrombocytopenic Purpura Associated with Pneumococcal Sepsis Canadian Journal of Infectious Diseases |
| title | Thrombotic Thrombocytopenic Purpura Associated with Pneumococcal Sepsis |
| title_full | Thrombotic Thrombocytopenic Purpura Associated with Pneumococcal Sepsis |
| title_fullStr | Thrombotic Thrombocytopenic Purpura Associated with Pneumococcal Sepsis |
| title_full_unstemmed | Thrombotic Thrombocytopenic Purpura Associated with Pneumococcal Sepsis |
| title_short | Thrombotic Thrombocytopenic Purpura Associated with Pneumococcal Sepsis |
| title_sort | thrombotic thrombocytopenic purpura associated with pneumococcal sepsis |
| url | http://dx.doi.org/10.1155/1993/921521 |
| work_keys_str_mv | AT jeffreyrschriber thromboticthrombocytopenicpurpuraassociatedwithpneumococcalsepsis AT johnjfreedman thromboticthrombocytopenicpurpuraassociatedwithpneumococcalsepsis AT josephmbrandwein thromboticthrombocytopenicpurpuraassociatedwithpneumococcalsepsis |