Determination of Gypenoside A and Gypenoside XLIX in Rat Plasma by UPLC-MS/MS and Applied to the Pharmacokinetics and Bioavailability

In this work, a UPLC-MS/MS method was developed for the determination of gypenoside A and gypenoside XLIX in rat plasma. For chromatographic separation, a UPLC BEH C18 column was employed, the mobile phase comprised acetonitrile: water (w/0.1% formic acid), and the elution time was 4 min. Detection...

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Bibliographic Details
Main Authors: Yan He, Qishun Liang, Lvqi Luo, Yifan He, Xueli Huang, Congcong Wen
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:International Journal of Analytical Chemistry
Online Access:http://dx.doi.org/10.1155/2022/6734408
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