Long-Term Intravenous Ketamine for Analgesia in a Child with Severe Chronic Intestinal Graft versus Host Disease
Ketamine is reported to be an effective adjuvant to opioids in the treatment of refractory cancer pain; however, the use of high doses of ketamine for extended periods in pediatric patients has not been described. We present a five-year-old male with grade IV intestinal GVHD whose abdominal pain req...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
|
| Series: | Case Reports in Anesthesiology |
| Online Access: | http://dx.doi.org/10.1155/2015/834168 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850216191329566720 |
|---|---|
| author | Jennifer Busse Leroy Phillips William Schechter |
| author_facet | Jennifer Busse Leroy Phillips William Schechter |
| author_sort | Jennifer Busse |
| collection | DOAJ |
| description | Ketamine is reported to be an effective adjuvant to opioids in the treatment of refractory cancer pain; however, the use of high doses of ketamine for extended periods in pediatric patients has not been described. We present a five-year-old male with grade IV intestinal GVHD whose abdominal pain required both hydromorphone and ketamine for a period of over four months. There was no evidence of hepatotoxicity, hemorrhagic cystitis, or other adverse effects. Possible withdrawal symptoms were mild and were readily mitigated by gradually weaning ketamine. |
| format | Article |
| id | doaj-art-3e096d9316f444d995afb07497d723bd |
| institution | OA Journals |
| issn | 2090-6382 2090-6390 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Anesthesiology |
| spelling | doaj-art-3e096d9316f444d995afb07497d723bd2025-08-20T02:08:23ZengWileyCase Reports in Anesthesiology2090-63822090-63902015-01-01201510.1155/2015/834168834168Long-Term Intravenous Ketamine for Analgesia in a Child with Severe Chronic Intestinal Graft versus Host DiseaseJennifer Busse0Leroy Phillips1William Schechter2Anesthesiology, Morgan Stanley Children’s Hospital at Columbia University, New York, NY 10032, USAAnesthesiology, New York University Langone Medical Center, New York, NY 10016, USAAnesthesiology and Pediatrics, Morgan Stanley Children’s Hospital at Columbia University, New York, NY 10032, USAKetamine is reported to be an effective adjuvant to opioids in the treatment of refractory cancer pain; however, the use of high doses of ketamine for extended periods in pediatric patients has not been described. We present a five-year-old male with grade IV intestinal GVHD whose abdominal pain required both hydromorphone and ketamine for a period of over four months. There was no evidence of hepatotoxicity, hemorrhagic cystitis, or other adverse effects. Possible withdrawal symptoms were mild and were readily mitigated by gradually weaning ketamine.http://dx.doi.org/10.1155/2015/834168 |
| spellingShingle | Jennifer Busse Leroy Phillips William Schechter Long-Term Intravenous Ketamine for Analgesia in a Child with Severe Chronic Intestinal Graft versus Host Disease Case Reports in Anesthesiology |
| title | Long-Term Intravenous Ketamine for Analgesia in a Child with Severe Chronic Intestinal Graft versus Host Disease |
| title_full | Long-Term Intravenous Ketamine for Analgesia in a Child with Severe Chronic Intestinal Graft versus Host Disease |
| title_fullStr | Long-Term Intravenous Ketamine for Analgesia in a Child with Severe Chronic Intestinal Graft versus Host Disease |
| title_full_unstemmed | Long-Term Intravenous Ketamine for Analgesia in a Child with Severe Chronic Intestinal Graft versus Host Disease |
| title_short | Long-Term Intravenous Ketamine for Analgesia in a Child with Severe Chronic Intestinal Graft versus Host Disease |
| title_sort | long term intravenous ketamine for analgesia in a child with severe chronic intestinal graft versus host disease |
| url | http://dx.doi.org/10.1155/2015/834168 |
| work_keys_str_mv | AT jenniferbusse longtermintravenousketamineforanalgesiainachildwithseverechronicintestinalgraftversushostdisease AT leroyphillips longtermintravenousketamineforanalgesiainachildwithseverechronicintestinalgraftversushostdisease AT williamschechter longtermintravenousketamineforanalgesiainachildwithseverechronicintestinalgraftversushostdisease |