Rapid and Environmentally‐Friendly Synthesis of Thiazolidinone Analogues in Deep Eutectic Solvent Complemented with Computational Studies

Abstract A greener, safer, and more efficient methodology for the synthesis of (Z)‐5‐benzylidene‐2‐thioxothiazolidin‐4‐ones (3 a–u) and (Z)‐5‐benzylidenethiazolidine‐2,4‐diones (4 a–i) has been developed. The deep eutectic solvent (DES) ZnCl2/urea used as a greener solvent as well as a catalyst in t...

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Bibliographic Details
Main Authors: Gobind Kumar, Pule Seboletswe, Nontobeko Gcabashe, Sanjeev Dhawan, Neha Manhas, Gaurav Bhargava, Rupesh Kumar, Parvesh Singh
Format: Article
Language:English
Published: Wiley-VCH 2025-02-01
Series:ChemistryOpen
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Online Access:https://doi.org/10.1002/open.202400198
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