Frugal Droplet Microfluidics Using Consumer Opto-Electronics.
The maker movement has shown how off-the-shelf devices can be combined to perform operations that, until recently, required expensive specialized equipment. Applying this philosophy to microfluidic devices can play a fundamental role in disseminating these technologies outside specialist labs and in...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2016-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0161490&type=printable |
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| author | Caroline Frot Nicolas Taccoen Charles N Baroud |
| author_facet | Caroline Frot Nicolas Taccoen Charles N Baroud |
| author_sort | Caroline Frot |
| collection | DOAJ |
| description | The maker movement has shown how off-the-shelf devices can be combined to perform operations that, until recently, required expensive specialized equipment. Applying this philosophy to microfluidic devices can play a fundamental role in disseminating these technologies outside specialist labs and into industrial use. Here we show how nanoliter droplets can be manipulated using a commercial DVD writer, interfaced with an Arduino electronic controller. We couple the optical setup with a droplet generation and manipulation device based on the "confinement gradients" approach. This device uses regions of different depths to generate and transport the droplets, which further simplifies the operation and reduces the need for precise flow control. The use of robust consumer electronics, combined with open source hardware, leads to a great reduction in the price of the device, as well as its footprint, without reducing its performance compared with the laboratory setup. |
| format | Article |
| id | doaj-art-3dfb6b519aa5472f968ec34af62e18a1 |
| institution | OA Journals |
| issn | 1932-6203 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-3dfb6b519aa5472f968ec34af62e18a12025-08-20T02:31:59ZengPublic Library of Science (PLoS)PLoS ONE1932-62032016-01-01118e016149010.1371/journal.pone.0161490Frugal Droplet Microfluidics Using Consumer Opto-Electronics.Caroline FrotNicolas TaccoenCharles N BaroudThe maker movement has shown how off-the-shelf devices can be combined to perform operations that, until recently, required expensive specialized equipment. Applying this philosophy to microfluidic devices can play a fundamental role in disseminating these technologies outside specialist labs and into industrial use. Here we show how nanoliter droplets can be manipulated using a commercial DVD writer, interfaced with an Arduino electronic controller. We couple the optical setup with a droplet generation and manipulation device based on the "confinement gradients" approach. This device uses regions of different depths to generate and transport the droplets, which further simplifies the operation and reduces the need for precise flow control. The use of robust consumer electronics, combined with open source hardware, leads to a great reduction in the price of the device, as well as its footprint, without reducing its performance compared with the laboratory setup.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0161490&type=printable |
| spellingShingle | Caroline Frot Nicolas Taccoen Charles N Baroud Frugal Droplet Microfluidics Using Consumer Opto-Electronics. PLoS ONE |
| title | Frugal Droplet Microfluidics Using Consumer Opto-Electronics. |
| title_full | Frugal Droplet Microfluidics Using Consumer Opto-Electronics. |
| title_fullStr | Frugal Droplet Microfluidics Using Consumer Opto-Electronics. |
| title_full_unstemmed | Frugal Droplet Microfluidics Using Consumer Opto-Electronics. |
| title_short | Frugal Droplet Microfluidics Using Consumer Opto-Electronics. |
| title_sort | frugal droplet microfluidics using consumer opto electronics |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0161490&type=printable |
| work_keys_str_mv | AT carolinefrot frugaldropletmicrofluidicsusingconsumeroptoelectronics AT nicolastaccoen frugaldropletmicrofluidicsusingconsumeroptoelectronics AT charlesnbaroud frugaldropletmicrofluidicsusingconsumeroptoelectronics |