Recent Advances in Chiral Gold Nanomaterials: From Synthesis to Applications

In recent years, the field of chiral gold nanomaterials has witnessed significant advancements driven by their unique properties and diverse applications in various scientific domains. This review provides an in-depth examination of the synthesis methodologies and evolving applications of chiral gol...

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Main Authors: Huangsiyu Chen, Changlong Hao
Format: Article
Language:English
Published: MDPI AG 2025-02-01
Series:Molecules
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Online Access:https://www.mdpi.com/1420-3049/30/4/829
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author Huangsiyu Chen
Changlong Hao
author_facet Huangsiyu Chen
Changlong Hao
author_sort Huangsiyu Chen
collection DOAJ
description In recent years, the field of chiral gold nanomaterials has witnessed significant advancements driven by their unique properties and diverse applications in various scientific domains. This review provides an in-depth examination of the synthesis methodologies and evolving applications of chiral gold nanomaterials, which have emerged as vital tools in areas such as antibacterial therapies, biosensing, catalysis, and nanomedicine. We start by discussing various synthesis techniques, focused on seed-mediated growth and circularly polarized light-assisted methods, each contributing to the controlled synthesis of chiral gold nanostructures with tailored optical activities. This review further delves into the applications of these nanomaterials, showcasing their potential in combating antibiotic-resistant bacteria, improving cancer immunotherapy, promoting tissue regeneration, and enabling precise biosensing through enhanced sensitivity and selectivity. We highlight the fundamental principles of chirality and its critical role in biological systems, emphasizing the importance of chiral gold nanomaterials in enhancing optical signals and facilitating molecular interactions. By consolidating recent findings and methodologies, this review endeavors to illuminate the promising future of chiral gold nanomaterials and their critical role in addressing contemporary scientific challenges.
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spelling doaj-art-3df8d4b32cba4f4dbd93fa5f07082b082025-08-20T02:44:35ZengMDPI AGMolecules1420-30492025-02-0130482910.3390/molecules30040829Recent Advances in Chiral Gold Nanomaterials: From Synthesis to ApplicationsHuangsiyu Chen0Changlong Hao1School of Food Science and Technology, State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, ChinaSchool of Food Science and Technology, State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi 214122, ChinaIn recent years, the field of chiral gold nanomaterials has witnessed significant advancements driven by their unique properties and diverse applications in various scientific domains. This review provides an in-depth examination of the synthesis methodologies and evolving applications of chiral gold nanomaterials, which have emerged as vital tools in areas such as antibacterial therapies, biosensing, catalysis, and nanomedicine. We start by discussing various synthesis techniques, focused on seed-mediated growth and circularly polarized light-assisted methods, each contributing to the controlled synthesis of chiral gold nanostructures with tailored optical activities. This review further delves into the applications of these nanomaterials, showcasing their potential in combating antibiotic-resistant bacteria, improving cancer immunotherapy, promoting tissue regeneration, and enabling precise biosensing through enhanced sensitivity and selectivity. We highlight the fundamental principles of chirality and its critical role in biological systems, emphasizing the importance of chiral gold nanomaterials in enhancing optical signals and facilitating molecular interactions. By consolidating recent findings and methodologies, this review endeavors to illuminate the promising future of chiral gold nanomaterials and their critical role in addressing contemporary scientific challenges.https://www.mdpi.com/1420-3049/30/4/829chiralgold nanomaterialssynthesissensorcatalysisnanomedicine
spellingShingle Huangsiyu Chen
Changlong Hao
Recent Advances in Chiral Gold Nanomaterials: From Synthesis to Applications
Molecules
chiral
gold nanomaterials
synthesis
sensor
catalysis
nanomedicine
title Recent Advances in Chiral Gold Nanomaterials: From Synthesis to Applications
title_full Recent Advances in Chiral Gold Nanomaterials: From Synthesis to Applications
title_fullStr Recent Advances in Chiral Gold Nanomaterials: From Synthesis to Applications
title_full_unstemmed Recent Advances in Chiral Gold Nanomaterials: From Synthesis to Applications
title_short Recent Advances in Chiral Gold Nanomaterials: From Synthesis to Applications
title_sort recent advances in chiral gold nanomaterials from synthesis to applications
topic chiral
gold nanomaterials
synthesis
sensor
catalysis
nanomedicine
url https://www.mdpi.com/1420-3049/30/4/829
work_keys_str_mv AT huangsiyuchen recentadvancesinchiralgoldnanomaterialsfromsynthesistoapplications
AT changlonghao recentadvancesinchiralgoldnanomaterialsfromsynthesistoapplications