Invasive Tests for Helicobacter Pylori in Children

One of the primary indications for upper gastrointestinal (GI) endoscopy in children is the presence of persistent and severe upper abdominal symptoms. Upper GI endoscopies are performed to allow the physician to confirm or rule out upper GI pathology. Additionally, upper GI endoscopies with mucosal...

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Main Author: Hien Q Huynh
Format: Article
Language:English
Published: Wiley 2005-01-01
Series:Canadian Journal of Gastroenterology
Online Access:http://dx.doi.org/10.1155/2005/514280
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author Hien Q Huynh
author_facet Hien Q Huynh
author_sort Hien Q Huynh
collection DOAJ
description One of the primary indications for upper gastrointestinal (GI) endoscopy in children is the presence of persistent and severe upper abdominal symptoms. Upper GI endoscopies are performed to allow the physician to confirm or rule out upper GI pathology. Additionally, upper GI endoscopies with mucosal biopsies are the gold standard for the diagnosis of Helicobacter pylori infection and its complications in children. The gastric biopsies can be used for the rapid urease test, histological examination and bacterial culture to determine antibiotic sensitivity. DNA extracted in these biopsies can also be subjected to genotyping using molecular methods to determine the presence of H pylori infection, antibiotic resistance mutations and H pylori virulence factors.
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spelling doaj-art-3df7847039e9477cb942bf92cfde32472025-08-20T03:55:40ZengWileyCanadian Journal of Gastroenterology0835-79002005-01-0119742943210.1155/2005/514280Invasive Tests for Helicobacter Pylori in ChildrenHien Q Huynh0Division of Pediatric Gastroenterology and Nutrition, Department of Pediatrics, Stollery Children’s Hospital, University of Alberta, Edmonton, Alberta, CanadaOne of the primary indications for upper gastrointestinal (GI) endoscopy in children is the presence of persistent and severe upper abdominal symptoms. Upper GI endoscopies are performed to allow the physician to confirm or rule out upper GI pathology. Additionally, upper GI endoscopies with mucosal biopsies are the gold standard for the diagnosis of Helicobacter pylori infection and its complications in children. The gastric biopsies can be used for the rapid urease test, histological examination and bacterial culture to determine antibiotic sensitivity. DNA extracted in these biopsies can also be subjected to genotyping using molecular methods to determine the presence of H pylori infection, antibiotic resistance mutations and H pylori virulence factors.http://dx.doi.org/10.1155/2005/514280
spellingShingle Hien Q Huynh
Invasive Tests for Helicobacter Pylori in Children
Canadian Journal of Gastroenterology
title Invasive Tests for Helicobacter Pylori in Children
title_full Invasive Tests for Helicobacter Pylori in Children
title_fullStr Invasive Tests for Helicobacter Pylori in Children
title_full_unstemmed Invasive Tests for Helicobacter Pylori in Children
title_short Invasive Tests for Helicobacter Pylori in Children
title_sort invasive tests for helicobacter pylori in children
url http://dx.doi.org/10.1155/2005/514280
work_keys_str_mv AT hienqhuynh invasivetestsforhelicobacterpyloriinchildren