Cardiometabolic Biomarkers in Young Black Girls: Relations to Body Fatness and Aerobic Fitness, and Effects of a Randomized Physical Activity Trial

There is little evidence from randomized trials showing that physical activity alone influences biomarker profiles in youths. This study tested two hypotheses: (i) that elevated body fatness and poor fitness would be associated with unfavorable levels of cardiometabolic biomarkers in 8–12-y-old blac...

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Main Authors: Bernard Gutin, Ryan A. Harris, Cheryl A. Howe, Maribeth H. Johnson, Haidong Zhu, Yanbin Dong
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:International Journal of Pediatrics
Online Access:http://dx.doi.org/10.1155/2011/219268
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author Bernard Gutin
Ryan A. Harris
Cheryl A. Howe
Maribeth H. Johnson
Haidong Zhu
Yanbin Dong
author_facet Bernard Gutin
Ryan A. Harris
Cheryl A. Howe
Maribeth H. Johnson
Haidong Zhu
Yanbin Dong
author_sort Bernard Gutin
collection DOAJ
description There is little evidence from randomized trials showing that physical activity alone influences biomarker profiles in youths. This study tested two hypotheses: (i) that elevated body fatness and poor fitness would be associated with unfavorable levels of cardiometabolic biomarkers in 8–12-y-old black girls (n=242) and (ii) that a 10-mo PA intervention would have favorable effects on the fatness-related cardiometabolic biomarkers. At baseline, all fatness indices (i.e., percent body fat, visceral adipose tissue, BMI, and waist circumference) were significantly (P<0.05) associated with unfavorable levels of insulin, glucose, systolic BP, diastolic BP, triglycerides, C-reactive protein (CRP), and fibrinogen. Aerobic fitness was significantly (P<0.05) associated with favorable levels of insulin, CRP, fibrinogen, and HDL2. The PA intervention had significant and favorable effects on fitness, fatness, and two biomarkers—resting heart rate and LDL cholesterol. More research is needed to clarify what types of interventions can enhance the cardiometabolic health of youths.
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spelling doaj-art-3df559c19fdf4e55868037558d617f712025-08-20T03:55:40ZengWileyInternational Journal of Pediatrics1687-97401687-97592011-01-01201110.1155/2011/219268219268Cardiometabolic Biomarkers in Young Black Girls: Relations to Body Fatness and Aerobic Fitness, and Effects of a Randomized Physical Activity TrialBernard Gutin0Ryan A. Harris1Cheryl A. Howe2Maribeth H. Johnson3Haidong Zhu4Yanbin Dong5Georgia Prevention Institute, Department of Pediatrics, Georgia Health Sciences University (Formerly the Medical College of Georgia), Augusta, GA 30912, USAGeorgia Prevention Institute, Department of Pediatrics, Georgia Health Sciences University (Formerly the Medical College of Georgia), Augusta, GA 30912, USAGeorgia Prevention Institute, Department of Pediatrics, Georgia Health Sciences University (Formerly the Medical College of Georgia), Augusta, GA 30912, USADepartment of Biostatistics, Georgia Health Sciences University, Augusta, GA 30912, USAGeorgia Prevention Institute, Department of Pediatrics, Georgia Health Sciences University (Formerly the Medical College of Georgia), Augusta, GA 30912, USAGeorgia Prevention Institute, Department of Pediatrics, Georgia Health Sciences University (Formerly the Medical College of Georgia), Augusta, GA 30912, USAThere is little evidence from randomized trials showing that physical activity alone influences biomarker profiles in youths. This study tested two hypotheses: (i) that elevated body fatness and poor fitness would be associated with unfavorable levels of cardiometabolic biomarkers in 8–12-y-old black girls (n=242) and (ii) that a 10-mo PA intervention would have favorable effects on the fatness-related cardiometabolic biomarkers. At baseline, all fatness indices (i.e., percent body fat, visceral adipose tissue, BMI, and waist circumference) were significantly (P<0.05) associated with unfavorable levels of insulin, glucose, systolic BP, diastolic BP, triglycerides, C-reactive protein (CRP), and fibrinogen. Aerobic fitness was significantly (P<0.05) associated with favorable levels of insulin, CRP, fibrinogen, and HDL2. The PA intervention had significant and favorable effects on fitness, fatness, and two biomarkers—resting heart rate and LDL cholesterol. More research is needed to clarify what types of interventions can enhance the cardiometabolic health of youths.http://dx.doi.org/10.1155/2011/219268
spellingShingle Bernard Gutin
Ryan A. Harris
Cheryl A. Howe
Maribeth H. Johnson
Haidong Zhu
Yanbin Dong
Cardiometabolic Biomarkers in Young Black Girls: Relations to Body Fatness and Aerobic Fitness, and Effects of a Randomized Physical Activity Trial
International Journal of Pediatrics
title Cardiometabolic Biomarkers in Young Black Girls: Relations to Body Fatness and Aerobic Fitness, and Effects of a Randomized Physical Activity Trial
title_full Cardiometabolic Biomarkers in Young Black Girls: Relations to Body Fatness and Aerobic Fitness, and Effects of a Randomized Physical Activity Trial
title_fullStr Cardiometabolic Biomarkers in Young Black Girls: Relations to Body Fatness and Aerobic Fitness, and Effects of a Randomized Physical Activity Trial
title_full_unstemmed Cardiometabolic Biomarkers in Young Black Girls: Relations to Body Fatness and Aerobic Fitness, and Effects of a Randomized Physical Activity Trial
title_short Cardiometabolic Biomarkers in Young Black Girls: Relations to Body Fatness and Aerobic Fitness, and Effects of a Randomized Physical Activity Trial
title_sort cardiometabolic biomarkers in young black girls relations to body fatness and aerobic fitness and effects of a randomized physical activity trial
url http://dx.doi.org/10.1155/2011/219268
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