Targeted Prostate Health Checks, a novel system to identify men with prostate cancer—A pilot study

Abstract Objectives The objective of this study is to report the pilot phase of the Targeted Prostate Health Check programme that aims to identify men in the Surrey and Sussex region who have prostate cancer and who failed to be detected during the Covid era. Subjects and methods Men aged 50 to 70,...

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Main Authors: Stephen Langley, Jeremy Goad, Stephanie Bell, Lee Foster, Catherine Hodges, Marc Laniado, Michele Pietrasik, Alison Rooke, Matthew Knight, Edward Bosonnet, Simon Bott
Format: Article
Language:English
Published: Wiley 2024-10-01
Series:BJUI Compass
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Online Access:https://doi.org/10.1002/bco2.416
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author Stephen Langley
Jeremy Goad
Stephanie Bell
Lee Foster
Catherine Hodges
Marc Laniado
Michele Pietrasik
Alison Rooke
Matthew Knight
Edward Bosonnet
Simon Bott
author_facet Stephen Langley
Jeremy Goad
Stephanie Bell
Lee Foster
Catherine Hodges
Marc Laniado
Michele Pietrasik
Alison Rooke
Matthew Knight
Edward Bosonnet
Simon Bott
author_sort Stephen Langley
collection DOAJ
description Abstract Objectives The objective of this study is to report the pilot phase of the Targeted Prostate Health Check programme that aims to identify men in the Surrey and Sussex region who have prostate cancer and who failed to be detected during the Covid era. Subjects and methods Men aged 50 to 70, or 45 to 70 if Black or with a family history of prostate cancer, were identified from participating general practitioner (GP) records. Short message service (SMS) texts invited men to visit www.talkprostate.co.uk for information on prostate cancer and give consent to prostate‐specific antigen (PSA) checks coordinated by a third‐party virtual healthcare provider. Elevated age‐related PSA levels, or levels below age‐related thresholds but at 3 ng/mL or more, triggered referral to a rapid access urology clinic. GPs were informed of the results. Results From 1842 text messages inviting 1549 people, 544 men consented to a PSA check. From 500 phlebotomy appointments, 485 (30% of invited men) took the PSA test of whom 68 (14%) were referred with an elevated PSA. After clinical review with multiparametric magnetic resonance imaging (mp‐MRI), 22 patients underwent transperineal biopsies, and prostate cancer was detected in 18 men of whom 17 (95%) had clinically significant cancer. Conclusion Our Targeted Prostate Cancer Health Check system identifies men at risk without burdening primary care. Awareness on prostate cancer risk was raised in 1549 invited men, half of whom were further educated via the registration website. One third of invited men were checked in whom clinically significant prostate cancer was found in 3.5%.
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spelling doaj-art-3dee28a26c4b418c8238f2ade26c7d7e2025-08-20T02:40:30ZengWileyBJUI Compass2688-45262024-10-015101083108910.1002/bco2.416Targeted Prostate Health Checks, a novel system to identify men with prostate cancer—A pilot studyStephen Langley0Jeremy Goad1Stephanie Bell2Lee Foster3Catherine Hodges4Marc Laniado5Michele Pietrasik6Alison Rooke7Matthew Knight8Edward Bosonnet9Simon Bott10The Stokes Centre for Urology Royal Surrey Hospital NHS Foundation Trust Guildford UKMedefer Ltd London UKSurrey and Sussex Cancer Alliance Guildford UKSurrey and Sussex Cancer Alliance Guildford UKSurrey Primary Care Lead Surrey & Sussex Cancer Alliance Guildford UKWexham Park Hospital Slough Berkshire UKThe Stokes Centre for Urology Royal Surrey Hospital NHS Foundation Trust Guildford UKThe Stokes Centre for Urology Royal Surrey Hospital NHS Foundation Trust Guildford UKMedefer Ltd London UKMedefer Ltd London UKFrimley Park Hospital, Frimley Health NHS Foundation Trust Frimley UKAbstract Objectives The objective of this study is to report the pilot phase of the Targeted Prostate Health Check programme that aims to identify men in the Surrey and Sussex region who have prostate cancer and who failed to be detected during the Covid era. Subjects and methods Men aged 50 to 70, or 45 to 70 if Black or with a family history of prostate cancer, were identified from participating general practitioner (GP) records. Short message service (SMS) texts invited men to visit www.talkprostate.co.uk for information on prostate cancer and give consent to prostate‐specific antigen (PSA) checks coordinated by a third‐party virtual healthcare provider. Elevated age‐related PSA levels, or levels below age‐related thresholds but at 3 ng/mL or more, triggered referral to a rapid access urology clinic. GPs were informed of the results. Results From 1842 text messages inviting 1549 people, 544 men consented to a PSA check. From 500 phlebotomy appointments, 485 (30% of invited men) took the PSA test of whom 68 (14%) were referred with an elevated PSA. After clinical review with multiparametric magnetic resonance imaging (mp‐MRI), 22 patients underwent transperineal biopsies, and prostate cancer was detected in 18 men of whom 17 (95%) had clinically significant cancer. Conclusion Our Targeted Prostate Cancer Health Check system identifies men at risk without burdening primary care. Awareness on prostate cancer risk was raised in 1549 invited men, half of whom were further educated via the registration website. One third of invited men were checked in whom clinically significant prostate cancer was found in 3.5%.https://doi.org/10.1002/bco2.416health checkmultiparametric‐MRIprostate cancerprostate‐specific antigenPSAtransperineal biopsy
spellingShingle Stephen Langley
Jeremy Goad
Stephanie Bell
Lee Foster
Catherine Hodges
Marc Laniado
Michele Pietrasik
Alison Rooke
Matthew Knight
Edward Bosonnet
Simon Bott
Targeted Prostate Health Checks, a novel system to identify men with prostate cancer—A pilot study
BJUI Compass
health check
multiparametric‐MRI
prostate cancer
prostate‐specific antigen
PSA
transperineal biopsy
title Targeted Prostate Health Checks, a novel system to identify men with prostate cancer—A pilot study
title_full Targeted Prostate Health Checks, a novel system to identify men with prostate cancer—A pilot study
title_fullStr Targeted Prostate Health Checks, a novel system to identify men with prostate cancer—A pilot study
title_full_unstemmed Targeted Prostate Health Checks, a novel system to identify men with prostate cancer—A pilot study
title_short Targeted Prostate Health Checks, a novel system to identify men with prostate cancer—A pilot study
title_sort targeted prostate health checks a novel system to identify men with prostate cancer a pilot study
topic health check
multiparametric‐MRI
prostate cancer
prostate‐specific antigen
PSA
transperineal biopsy
url https://doi.org/10.1002/bco2.416
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