Syndrome of mutual buffering in patients with rectal fistulas in combination with diabetes mellitus
BACKGROUND: The results of surgical treatment of rectal fistulas (RF) directly depend on the accuracy of their diagnosis and the detection of a concomitant disease, such as diabetes mellitus (DM). To improve the results of surgical treatment, it is necessary to take into account the mutual influence...
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Endocrinology Research Centre
2024-07-01
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| Series: | Сахарный диабет |
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| Online Access: | https://www.dia-endojournals.ru/jour/article/view/12959 |
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| author | D. K. Mukhabbatov M. K. Gulov B. M. Khamroev S. G. Ali-Zade N. F. Niyazova |
| author_facet | D. K. Mukhabbatov M. K. Gulov B. M. Khamroev S. G. Ali-Zade N. F. Niyazova |
| author_sort | D. K. Mukhabbatov |
| collection | DOAJ |
| description | BACKGROUND: The results of surgical treatment of rectal fistulas (RF) directly depend on the accuracy of their diagnosis and the detection of a concomitant disease, such as diabetes mellitus (DM). To improve the results of surgical treatment, it is necessary to take into account the mutual influence of RF and DM, which can aggravate each other’s course.AIM: The study of the features of the course of RF against the background of DM and the assessment of their mutually aggravating influence.MATERIALS AND METHODS: 120 patients with RF were studied, which were divided into two groups: the main group (MG) included 60 patients with DM, the control group (CG) also included 60 patients without DM.RESULTS: In both groups, patients with transsphincteric RF dominated: 39 (65.0%) in the MG and 38 (63.3%) in the CG. Recurrent SPC prevailed in patients with DM (30.0% versus 15.0%), which indicates a more complex course of RF against the background of DM. It was found that in 17 (28.3%) patients, the stage of diabetes compensation after the formation of a fistula with a purulent cavity in the pararectal tissue passed into the stage of subcompensation and, due to an unstable decrease in blood sugar levels, it was necessary to replace tableted antidiabetic drugs with injectable insulin, which says about the deterioration of the course of diabetes against the background of chronic purulent inflammation in the pararectal tissue. The results of the study showed the presence of a direct correlation between the course of chronic paraproctitis and the stage of DM (r=0.50552, p<0.001), which indicates the presence of a mutual burden syndrome.CONCLUSION: DM and chronic paraproctitis have a mutually aggravating effect on each other. Our results indicate the presence of a syndrome of mutual aggravation in patients with RF fistulas against the background of DM, which worsen the course of each other, which must be taken into account at the stages of diagnosis and preoperative preparation of patients to improve the immediate and long-term results of surgical treatment in this category of patients. |
| format | Article |
| id | doaj-art-3de796a6178f4ef58be22c697e8a32f2 |
| institution | OA Journals |
| issn | 2072-0351 2072-0378 |
| language | English |
| publishDate | 2024-07-01 |
| publisher | Endocrinology Research Centre |
| record_format | Article |
| series | Сахарный диабет |
| spelling | doaj-art-3de796a6178f4ef58be22c697e8a32f22025-08-20T02:29:39ZengEndocrinology Research CentreСахарный диабет2072-03512072-03782024-07-0127323324110.14341/DM1295911090Syndrome of mutual buffering in patients with rectal fistulas in combination with diabetes mellitusD. K. Mukhabbatov0M. K. Gulov1B. M. Khamroev2S. G. Ali-Zade3N. F. Niyazova4Avicenna Tajik State Medical UniversityAvicenna Tajik State Medical UniversityAvicenna Tajik State Medical UniversityAvicenna Tajik State Medical UniversityAvicenna Tajik State Medical UniversityBACKGROUND: The results of surgical treatment of rectal fistulas (RF) directly depend on the accuracy of their diagnosis and the detection of a concomitant disease, such as diabetes mellitus (DM). To improve the results of surgical treatment, it is necessary to take into account the mutual influence of RF and DM, which can aggravate each other’s course.AIM: The study of the features of the course of RF against the background of DM and the assessment of their mutually aggravating influence.MATERIALS AND METHODS: 120 patients with RF were studied, which were divided into two groups: the main group (MG) included 60 patients with DM, the control group (CG) also included 60 patients without DM.RESULTS: In both groups, patients with transsphincteric RF dominated: 39 (65.0%) in the MG and 38 (63.3%) in the CG. Recurrent SPC prevailed in patients with DM (30.0% versus 15.0%), which indicates a more complex course of RF against the background of DM. It was found that in 17 (28.3%) patients, the stage of diabetes compensation after the formation of a fistula with a purulent cavity in the pararectal tissue passed into the stage of subcompensation and, due to an unstable decrease in blood sugar levels, it was necessary to replace tableted antidiabetic drugs with injectable insulin, which says about the deterioration of the course of diabetes against the background of chronic purulent inflammation in the pararectal tissue. The results of the study showed the presence of a direct correlation between the course of chronic paraproctitis and the stage of DM (r=0.50552, p<0.001), which indicates the presence of a mutual burden syndrome.CONCLUSION: DM and chronic paraproctitis have a mutually aggravating effect on each other. Our results indicate the presence of a syndrome of mutual aggravation in patients with RF fistulas against the background of DM, which worsen the course of each other, which must be taken into account at the stages of diagnosis and preoperative preparation of patients to improve the immediate and long-term results of surgical treatment in this category of patients.https://www.dia-endojournals.ru/jour/article/view/12959rectal fistulachronic paraproctitisrelapsediabetes mellitus |
| spellingShingle | D. K. Mukhabbatov M. K. Gulov B. M. Khamroev S. G. Ali-Zade N. F. Niyazova Syndrome of mutual buffering in patients with rectal fistulas in combination with diabetes mellitus Сахарный диабет rectal fistula chronic paraproctitis relapse diabetes mellitus |
| title | Syndrome of mutual buffering in patients with rectal fistulas in combination with diabetes mellitus |
| title_full | Syndrome of mutual buffering in patients with rectal fistulas in combination with diabetes mellitus |
| title_fullStr | Syndrome of mutual buffering in patients with rectal fistulas in combination with diabetes mellitus |
| title_full_unstemmed | Syndrome of mutual buffering in patients with rectal fistulas in combination with diabetes mellitus |
| title_short | Syndrome of mutual buffering in patients with rectal fistulas in combination with diabetes mellitus |
| title_sort | syndrome of mutual buffering in patients with rectal fistulas in combination with diabetes mellitus |
| topic | rectal fistula chronic paraproctitis relapse diabetes mellitus |
| url | https://www.dia-endojournals.ru/jour/article/view/12959 |
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