Acute depletion of complement C3 with cobra venom factor attenuates memory deficits induced by status epilepticus

Acute depletion of complement C3 with cobra venom factor attenuates memory deficits induced by status epilepticus

Abstract Objective Status epilepticus (SE) significantly increases the risk for the development of unprovoked seizures, memory loss, and temporal lobe epilepsy. Our prior studies showed that SE increases complement C3 signaling in the hippocampus, which parallels memory deficits. Additionally, C3 kn...

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Bibliographic Details
Main Authors: Nicole D. Schartz, Yibo Li, Alexandra L. Sommer, Amy L. Brewster
Format: Article
Language:English
Published: Wiley 2024-12-01
Series:Epilepsia Open
Subjects:
complement C3
hippocampus
memory
pilocarpine
status epilepticus
Online Access:https://doi.org/10.1002/epi4.13030
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