Design and synthesis of amino-substituted N-arylpiperidinyl-based inhibitors of the (immuno)proteasome
The constitutive proteasome and the immunoproteasome represent validated targets for pharmacological intervention in the context of various diseases, such as cancer, inflammation, and autoimmune diseases. The development of novel chemical scaffolds of non-peptidic nature, capable of inhibiting diffe...
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Main Authors: | Gobec Martina, Obreza Aleš, Jukič Marko, Baumgartner Ana, Mihelčič Nja, Potočnik Špela, Virant Julija, Mlinarič Irena, Stanislav Raščan, Sosič Gobec Izidor |
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Format: | Article |
Language: | English |
Published: |
Sciendo
2023-09-01
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Series: | Acta Pharmaceutica |
Subjects: | |
Online Access: | https://doi.org/10.2478/acph-2023-0032 |
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