Comprehensive analysis and validation of autophagy-related gene in rheumatoid arthritis

Comprehensive analysis and validation of autophagy-related gene in rheumatoid arthritis

BackgroundRheumatoid arthritis (RA) is a chronic autoimmune disease in which autophagy is pivotal in its pathogenesis. This study aims to identify autophagy-related genes associated with RA and investigate their functional roles.MethodsWe performed mRNA sequencing to identify differentially expresse...

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Bibliographic Details
Main Authors: Runrun Zhang, Wenhan Huang, Ting Zhao, Jintao Fang, Cen Chang, Dongyi He, Xinchang Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
rheumatoid arthritis
IRF4
autophagy
bioinformatics
machine learning
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1563911/full
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