Red blood cell distribution width is a short-term mortality predictor in middle-aged and older adults with hip fracture

Abstract Objective To study the relationship between red blood cell distribution width (RDW) and short-term mortality of hip fracture in middle-aged and older adults. Methods A retrospective cohort of electronic medical records at a single hospital over a 2-year period between 2020 and 2021. We rece...

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Main Authors: Xiao-feng Liu, Yong-qiang Zheng, Liang Lin, Zhen-yu Lin, Hong-peng Zhang, Xiao-peng Huang, Ze-feng Wang, Jin-shan Zhang
Format: Article
Language:English
Published: BMC 2025-03-01
Series:BMC Musculoskeletal Disorders
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Online Access:https://doi.org/10.1186/s12891-025-08499-x
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author Xiao-feng Liu
Yong-qiang Zheng
Liang Lin
Zhen-yu Lin
Hong-peng Zhang
Xiao-peng Huang
Ze-feng Wang
Jin-shan Zhang
author_facet Xiao-feng Liu
Yong-qiang Zheng
Liang Lin
Zhen-yu Lin
Hong-peng Zhang
Xiao-peng Huang
Ze-feng Wang
Jin-shan Zhang
author_sort Xiao-feng Liu
collection DOAJ
description Abstract Objective To study the relationship between red blood cell distribution width (RDW) and short-term mortality of hip fracture in middle-aged and older adults. Methods A retrospective cohort of electronic medical records at a single hospital over a 2-year period between 2020 and 2021. We received the records of 233 patients aged > 50 years who suffered from hip fracture. the clinical data including patients demographics, comorbidities at the time of admission, type of surgery, blood examination, 3-months mortality, 6-months mortality and 1-year mortality. the relationship between RDW and short-term mortality of hip fracture were analyzed. the cohort was then divided into two groups based on their RDW levels at the time of admission: low (RDW < 13.6%) and high (RDW ≥ 13.6%). Results Results the mean age was 78.03 ± 12.09 years; 64.81% were woman. At admission, 80 patients (34.33%) had high RDW levels and 153 patients (65.67%) had low RDW levels. there were no statistically significant differences between the groups with regard to sex, type of operation, duration of surgery and hospitalization length. Patients with high RDW had more comorbidities when compared to patients with low RDW levels (p < 0.05). All-cause mortality was higher for patients with high RDW levels, at 3 months (p < 0.05), 6 months (p < 0.05), and 12 months (p < 0.05). Conclusion RDW is significantly related with short-term mortality in hip fracture. The higher RDW, the higher risk of mortality.
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spelling doaj-art-3dc6f2595d254fc88f6c86ee6e01194d2025-08-20T03:01:54ZengBMCBMC Musculoskeletal Disorders1471-24742025-03-012611810.1186/s12891-025-08499-xRed blood cell distribution width is a short-term mortality predictor in middle-aged and older adults with hip fractureXiao-feng Liu0Yong-qiang Zheng1Liang Lin2Zhen-yu Lin3Hong-peng Zhang4Xiao-peng Huang5Ze-feng Wang6Jin-shan Zhang7Department of Orthopedics, Jinjiang Municipal Hospital (Shanghai Sixth People’s Hospital Fujian)Department of Orthopedics, Jinjiang Municipal Hospital (Shanghai Sixth People’s Hospital Fujian)Department of Orthopedics, Jinjiang Municipal Hospital (Shanghai Sixth People’s Hospital Fujian)Department of Orthopedics, Jinjiang Municipal Hospital (Shanghai Sixth People’s Hospital Fujian)Department of Orthopedics, Jinjiang Municipal Hospital (Shanghai Sixth People’s Hospital Fujian)Department of Orthopedics, Jinjiang Municipal Hospital (Shanghai Sixth People’s Hospital Fujian)Department of Orthopedics, Jinjiang Municipal Hospital (Shanghai Sixth People’s Hospital Fujian)Department of Orthopedics, Jinjiang Municipal Hospital (Shanghai Sixth People’s Hospital Fujian)Abstract Objective To study the relationship between red blood cell distribution width (RDW) and short-term mortality of hip fracture in middle-aged and older adults. Methods A retrospective cohort of electronic medical records at a single hospital over a 2-year period between 2020 and 2021. We received the records of 233 patients aged > 50 years who suffered from hip fracture. the clinical data including patients demographics, comorbidities at the time of admission, type of surgery, blood examination, 3-months mortality, 6-months mortality and 1-year mortality. the relationship between RDW and short-term mortality of hip fracture were analyzed. the cohort was then divided into two groups based on their RDW levels at the time of admission: low (RDW < 13.6%) and high (RDW ≥ 13.6%). Results Results the mean age was 78.03 ± 12.09 years; 64.81% were woman. At admission, 80 patients (34.33%) had high RDW levels and 153 patients (65.67%) had low RDW levels. there were no statistically significant differences between the groups with regard to sex, type of operation, duration of surgery and hospitalization length. Patients with high RDW had more comorbidities when compared to patients with low RDW levels (p < 0.05). All-cause mortality was higher for patients with high RDW levels, at 3 months (p < 0.05), 6 months (p < 0.05), and 12 months (p < 0.05). Conclusion RDW is significantly related with short-term mortality in hip fracture. The higher RDW, the higher risk of mortality.https://doi.org/10.1186/s12891-025-08499-xHip fractureRed blood cell distribution widthMiddle-aged and older adultsShort-term mortality
spellingShingle Xiao-feng Liu
Yong-qiang Zheng
Liang Lin
Zhen-yu Lin
Hong-peng Zhang
Xiao-peng Huang
Ze-feng Wang
Jin-shan Zhang
Red blood cell distribution width is a short-term mortality predictor in middle-aged and older adults with hip fracture
BMC Musculoskeletal Disorders
Hip fracture
Red blood cell distribution width
Middle-aged and older adults
Short-term mortality
title Red blood cell distribution width is a short-term mortality predictor in middle-aged and older adults with hip fracture
title_full Red blood cell distribution width is a short-term mortality predictor in middle-aged and older adults with hip fracture
title_fullStr Red blood cell distribution width is a short-term mortality predictor in middle-aged and older adults with hip fracture
title_full_unstemmed Red blood cell distribution width is a short-term mortality predictor in middle-aged and older adults with hip fracture
title_short Red blood cell distribution width is a short-term mortality predictor in middle-aged and older adults with hip fracture
title_sort red blood cell distribution width is a short term mortality predictor in middle aged and older adults with hip fracture
topic Hip fracture
Red blood cell distribution width
Middle-aged and older adults
Short-term mortality
url https://doi.org/10.1186/s12891-025-08499-x
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