Systemic Endothelial Function in Primary Open-Angle Glaucoma
Objective. We aimed to assess peripheral vascular endothelial function in open-angle glaucoma (POAG) by measuring flow-mediated dilatation (FMD). Materials and Methods. The study included 20 cases with POAG (group 1, mean age 58.68±13.3 years) and 30 healthy individuals (group 2,...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Journal of Ophthalmology |
| Online Access: | http://dx.doi.org/10.1155/2014/529082 |
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| author | Mustafa Atas Hasan Basri Arifoglu Arzu Seyhan Karatepe Hashas Bahadır Sarli Suleyman Demircan Ayse Ozkose Altan Goktas |
| author_facet | Mustafa Atas Hasan Basri Arifoglu Arzu Seyhan Karatepe Hashas Bahadır Sarli Suleyman Demircan Ayse Ozkose Altan Goktas |
| author_sort | Mustafa Atas |
| collection | DOAJ |
| description | Objective. We aimed to assess peripheral vascular endothelial function in
open-angle glaucoma (POAG) by measuring flow-mediated dilatation (FMD). Materials and Methods. The study included 20 cases with POAG (group 1, mean age 58.68±13.3 years) and 30 healthy individuals (group 2, mean age 58.68±13.6 years). In all cases, responses of endothelial function were assessed by a cardiologist through measurement of FMD following brachial artery occlusion. Results. Mean percent of FMD, an indicator of endothelial function, was found to be 11.9±4.2% in group 1 and 12.3±4.4% in group 2 (P=0.86). Conclusion. No impairment in systemic vascular function of cases with POAG suggests that POAG could be a local disorder rather than being a component of systemic disease. |
| format | Article |
| id | doaj-art-3dc11437e5d64c2a8eceb6bf9f257580 |
| institution | Kabale University |
| issn | 2090-004X 2090-0058 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Journal of Ophthalmology |
| spelling | doaj-art-3dc11437e5d64c2a8eceb6bf9f2575802025-02-03T01:29:16ZengWileyJournal of Ophthalmology2090-004X2090-00582014-01-01201410.1155/2014/529082529082Systemic Endothelial Function in Primary Open-Angle GlaucomaMustafa Atas0Hasan Basri Arifoglu1Arzu Seyhan Karatepe Hashas2Bahadır Sarli3Suleyman Demircan4Ayse Ozkose5Altan Goktas6Department of Ophthalmology and Vision Science, Kayseri Training and Research Hospital, Sanayi Mah. Atatürk Boulevard Hastane Street , No. 78, 38010 Kayseri, TurkeyDepartment of Ophthalmology and Vision Science, Kayseri Training and Research Hospital, Sanayi Mah. Atatürk Boulevard Hastane Street , No. 78, 38010 Kayseri, TurkeyDepartment of Ophthalmology and Vision Science, Kayseri Training and Research Hospital, Sanayi Mah. Atatürk Boulevard Hastane Street , No. 78, 38010 Kayseri, TurkeyDepartment of Cardiology, Kayseri Training and Research Hospital, 38010 Kayseri, TurkeyDepartment of Ophthalmology and Vision Science, Kayseri Training and Research Hospital, Sanayi Mah. Atatürk Boulevard Hastane Street , No. 78, 38010 Kayseri, TurkeyDepartment of Ophthalmology and Vision Science, Kayseri Training and Research Hospital, Sanayi Mah. Atatürk Boulevard Hastane Street , No. 78, 38010 Kayseri, TurkeyDepartment of Ophthalmology and Vision Science, Kayseri Training and Research Hospital, Sanayi Mah. Atatürk Boulevard Hastane Street , No. 78, 38010 Kayseri, TurkeyObjective. We aimed to assess peripheral vascular endothelial function in open-angle glaucoma (POAG) by measuring flow-mediated dilatation (FMD). Materials and Methods. The study included 20 cases with POAG (group 1, mean age 58.68±13.3 years) and 30 healthy individuals (group 2, mean age 58.68±13.6 years). In all cases, responses of endothelial function were assessed by a cardiologist through measurement of FMD following brachial artery occlusion. Results. Mean percent of FMD, an indicator of endothelial function, was found to be 11.9±4.2% in group 1 and 12.3±4.4% in group 2 (P=0.86). Conclusion. No impairment in systemic vascular function of cases with POAG suggests that POAG could be a local disorder rather than being a component of systemic disease.http://dx.doi.org/10.1155/2014/529082 |
| spellingShingle | Mustafa Atas Hasan Basri Arifoglu Arzu Seyhan Karatepe Hashas Bahadır Sarli Suleyman Demircan Ayse Ozkose Altan Goktas Systemic Endothelial Function in Primary Open-Angle Glaucoma Journal of Ophthalmology |
| title | Systemic Endothelial Function in Primary Open-Angle Glaucoma |
| title_full | Systemic Endothelial Function in Primary Open-Angle Glaucoma |
| title_fullStr | Systemic Endothelial Function in Primary Open-Angle Glaucoma |
| title_full_unstemmed | Systemic Endothelial Function in Primary Open-Angle Glaucoma |
| title_short | Systemic Endothelial Function in Primary Open-Angle Glaucoma |
| title_sort | systemic endothelial function in primary open angle glaucoma |
| url | http://dx.doi.org/10.1155/2014/529082 |
| work_keys_str_mv | AT mustafaatas systemicendothelialfunctioninprimaryopenangleglaucoma AT hasanbasriarifoglu systemicendothelialfunctioninprimaryopenangleglaucoma AT arzuseyhankaratepehashas systemicendothelialfunctioninprimaryopenangleglaucoma AT bahadırsarli systemicendothelialfunctioninprimaryopenangleglaucoma AT suleymandemircan systemicendothelialfunctioninprimaryopenangleglaucoma AT ayseozkose systemicendothelialfunctioninprimaryopenangleglaucoma AT altangoktas systemicendothelialfunctioninprimaryopenangleglaucoma |