Betalains protect various body organs through antioxidant and anti-inflammatory pathways
Betalains are natural coloring pigments with betalamic acid as the core structure of all subclasses. Besides their coloring properties, betalains exhibit various biological activities, including antioxidant and anti-inflammatory properties, which are highly imperative. Further in-vivo studies report...
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| Format: | Article |
| Language: | English |
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Tsinghua University Press
2024-05-01
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| Series: | Food Science and Human Wellness |
| Subjects: | |
| Online Access: | https://www.sciopen.com/article/10.26599/FSHW.2022.9250093 |
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| author | Nilesh Prakash Nirmal Seema Medhe Merina Dahal Pankaj Koirala Siriwan Nirmal Fahad Al-Asmari Baojun Xu |
| author_facet | Nilesh Prakash Nirmal Seema Medhe Merina Dahal Pankaj Koirala Siriwan Nirmal Fahad Al-Asmari Baojun Xu |
| author_sort | Nilesh Prakash Nirmal |
| collection | DOAJ |
| description | Betalains are natural coloring pigments with betalamic acid as the core structure of all subclasses. Besides their coloring properties, betalains exhibit various biological activities, including antioxidant and anti-inflammatory properties, which are highly imperative. Further in-vivo studies reported that betalains protect various body organs, leading to health enhancement. Body organs, including the heart, liver, kidney, lung, etc., are important for a healthy life. However, these organs can be affected or damaged by various stress factors, toxicants, and harmful substances. Recent studies have claimed that betalains could protect all vital organs of the body through antioxidant and anti-inflammatory mechanisms. This review article described the in-vivo antioxidant and anti-inflammatory activities of betalains in various cell-line or animal models. A comprehensive discussion has been provided on the mechanism of action of betalains in protecting various body organs, including cardio-protective effect, hepato-protective ability, renal protection capacity, repro-protective ability, neuro-protective effect, lung protection, and gut protection ability. Finally, future research directions and conclusions have been outlined. |
| format | Article |
| id | doaj-art-3dae68cce7e04534998687e520ce1b68 |
| institution | Kabale University |
| issn | 2097-0765 2213-4530 |
| language | English |
| publishDate | 2024-05-01 |
| publisher | Tsinghua University Press |
| record_format | Article |
| series | Food Science and Human Wellness |
| spelling | doaj-art-3dae68cce7e04534998687e520ce1b682025-01-10T06:54:23ZengTsinghua University PressFood Science and Human Wellness2097-07652213-45302024-05-011331109111710.26599/FSHW.2022.9250093Betalains protect various body organs through antioxidant and anti-inflammatory pathwaysNilesh Prakash Nirmal0Seema Medhe1Merina Dahal2Pankaj Koirala3Siriwan Nirmal4Fahad Al-Asmari5Baojun Xu6Institute of Nutrition, Mahidol University, Nakhon Pathom 73170, ThailandInstitute of Nutrition, Mahidol University, Nakhon Pathom 73170, ThailandDepartment of Nutrition and Dietetics, Central Campus of Technology, Tribhuvan University, Kathmandu 46000, NepalInstitute of Nutrition, Mahidol University, Nakhon Pathom 73170, ThailandDepartment of Adult Nursing, Faculty of Nursing, Burapha University, Chonburi 20131, ThailandDepartment of Food Science and Nutrition, College of Agriculture and Food Sciences, King Faisal University, Al-Ahsa 31982, Saudi ArabiaFood Science and Technology Program, Department of Life Sciences, BNU-HKBU United International College, Zhuhai 519088, ChinaBetalains are natural coloring pigments with betalamic acid as the core structure of all subclasses. Besides their coloring properties, betalains exhibit various biological activities, including antioxidant and anti-inflammatory properties, which are highly imperative. Further in-vivo studies reported that betalains protect various body organs, leading to health enhancement. Body organs, including the heart, liver, kidney, lung, etc., are important for a healthy life. However, these organs can be affected or damaged by various stress factors, toxicants, and harmful substances. Recent studies have claimed that betalains could protect all vital organs of the body through antioxidant and anti-inflammatory mechanisms. This review article described the in-vivo antioxidant and anti-inflammatory activities of betalains in various cell-line or animal models. A comprehensive discussion has been provided on the mechanism of action of betalains in protecting various body organs, including cardio-protective effect, hepato-protective ability, renal protection capacity, repro-protective ability, neuro-protective effect, lung protection, and gut protection ability. Finally, future research directions and conclusions have been outlined.https://www.sciopen.com/article/10.26599/FSHW.2022.9250093betalainsantioxidantanti-inflammatorybioactivitiesogans-protection |
| spellingShingle | Nilesh Prakash Nirmal Seema Medhe Merina Dahal Pankaj Koirala Siriwan Nirmal Fahad Al-Asmari Baojun Xu Betalains protect various body organs through antioxidant and anti-inflammatory pathways Food Science and Human Wellness betalains antioxidant anti-inflammatory bioactivities ogans-protection |
| title | Betalains protect various body organs through antioxidant and anti-inflammatory pathways |
| title_full | Betalains protect various body organs through antioxidant and anti-inflammatory pathways |
| title_fullStr | Betalains protect various body organs through antioxidant and anti-inflammatory pathways |
| title_full_unstemmed | Betalains protect various body organs through antioxidant and anti-inflammatory pathways |
| title_short | Betalains protect various body organs through antioxidant and anti-inflammatory pathways |
| title_sort | betalains protect various body organs through antioxidant and anti inflammatory pathways |
| topic | betalains antioxidant anti-inflammatory bioactivities ogans-protection |
| url | https://www.sciopen.com/article/10.26599/FSHW.2022.9250093 |
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