Deep Brain Stimulation Can Preserve Working Status in Parkinson’s Disease
Objectives. Our investigation aimed at evaluating if bilateral subthalamic deep brain stimulation (DBS) could preserve working capability in Parkinson’s disease (PD). Materials. We reviewed the data of 40 young (<60 year-old) PD patients who underwent DBS implantation and had at least 2 years of...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Parkinson's Disease |
| Online Access: | http://dx.doi.org/10.1155/2015/936865 |
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| author | Gabriella Deli István Balás Tamás Dóczi József Janszky Kázmér Karádi Zsuzsanna Aschermann Ferenc Nagy Attila Makkos Márton Kovács Edit Bosnyák Norbert Kovács Sámuel Komoly |
| author_facet | Gabriella Deli István Balás Tamás Dóczi József Janszky Kázmér Karádi Zsuzsanna Aschermann Ferenc Nagy Attila Makkos Márton Kovács Edit Bosnyák Norbert Kovács Sámuel Komoly |
| author_sort | Gabriella Deli |
| collection | DOAJ |
| description | Objectives. Our investigation aimed at evaluating if bilateral subthalamic deep brain stimulation (DBS) could preserve working capability in Parkinson’s disease (PD). Materials. We reviewed the data of 40 young (<60 year-old) PD patients who underwent DBS implantation and had at least 2 years of follow-up. Patients were categorized based on their working capability at time of surgery: “active job” group (n=20) and “no job” group (n=20). Baseline characteristics were comparable. Quality of life (EQ-5D) and presence of active job were evaluated preoperatively and 2 years postoperatively. Results. Although similar (approximately 50%) improvement was achieved in the severity of motor and major nonmotor symptoms in both groups, the postoperative quality of life was significantly better in the “active job” group (0.687 versus 0.587, medians, p<0.05). Majority (80%) of “active job” group members were able to preserve their job 2 years after the operation. However, only a minimal portion (5%) of the “no job” group members was able to return to the world of active employees (p<0.01). Conclusions. Although our study has several limitations, our results suggest that in patients with active job the appropriately “early” usage of DBS might help preserve working capability and gain higher improvement in quality of life. |
| format | Article |
| id | doaj-art-3dab06b14edd4e78809f2792bd3ea7fd |
| institution | OA Journals |
| issn | 2090-8083 2042-0080 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Parkinson's Disease |
| spelling | doaj-art-3dab06b14edd4e78809f2792bd3ea7fd2025-08-20T02:07:49ZengWileyParkinson's Disease2090-80832042-00802015-01-01201510.1155/2015/936865936865Deep Brain Stimulation Can Preserve Working Status in Parkinson’s DiseaseGabriella Deli0István Balás1Tamás Dóczi2József Janszky3Kázmér Karádi4Zsuzsanna Aschermann5Ferenc Nagy6Attila Makkos7Márton Kovács8Edit Bosnyák9Norbert Kovács10Sámuel Komoly11Department of Neurology, University of Pécs, Rét Utca 2, Pécs 7623, HungaryDepartment of Neurosurgery, University of Pécs, Rét Utca 2, Pécs 7623, HungaryDepartment of Neurosurgery, University of Pécs, Rét Utca 2, Pécs 7623, HungaryDepartment of Neurology, University of Pécs, Rét Utca 2, Pécs 7623, HungaryDepartment of Neurology, University of Pécs, Rét Utca 2, Pécs 7623, HungaryDepartment of Neurology, University of Pécs, Rét Utca 2, Pécs 7623, HungaryDepartment of Neurology, University of Pécs, Rét Utca 2, Pécs 7623, HungaryDepartment of Neurology, University of Pécs, Rét Utca 2, Pécs 7623, HungaryDepartment of Neurology, University of Pécs, Rét Utca 2, Pécs 7623, HungaryDepartment of Neurology, University of Pécs, Rét Utca 2, Pécs 7623, HungaryDepartment of Neurology, University of Pécs, Rét Utca 2, Pécs 7623, HungaryDepartment of Neurology, University of Pécs, Rét Utca 2, Pécs 7623, HungaryObjectives. Our investigation aimed at evaluating if bilateral subthalamic deep brain stimulation (DBS) could preserve working capability in Parkinson’s disease (PD). Materials. We reviewed the data of 40 young (<60 year-old) PD patients who underwent DBS implantation and had at least 2 years of follow-up. Patients were categorized based on their working capability at time of surgery: “active job” group (n=20) and “no job” group (n=20). Baseline characteristics were comparable. Quality of life (EQ-5D) and presence of active job were evaluated preoperatively and 2 years postoperatively. Results. Although similar (approximately 50%) improvement was achieved in the severity of motor and major nonmotor symptoms in both groups, the postoperative quality of life was significantly better in the “active job” group (0.687 versus 0.587, medians, p<0.05). Majority (80%) of “active job” group members were able to preserve their job 2 years after the operation. However, only a minimal portion (5%) of the “no job” group members was able to return to the world of active employees (p<0.01). Conclusions. Although our study has several limitations, our results suggest that in patients with active job the appropriately “early” usage of DBS might help preserve working capability and gain higher improvement in quality of life.http://dx.doi.org/10.1155/2015/936865 |
| spellingShingle | Gabriella Deli István Balás Tamás Dóczi József Janszky Kázmér Karádi Zsuzsanna Aschermann Ferenc Nagy Attila Makkos Márton Kovács Edit Bosnyák Norbert Kovács Sámuel Komoly Deep Brain Stimulation Can Preserve Working Status in Parkinson’s Disease Parkinson's Disease |
| title | Deep Brain Stimulation Can Preserve Working Status in Parkinson’s Disease |
| title_full | Deep Brain Stimulation Can Preserve Working Status in Parkinson’s Disease |
| title_fullStr | Deep Brain Stimulation Can Preserve Working Status in Parkinson’s Disease |
| title_full_unstemmed | Deep Brain Stimulation Can Preserve Working Status in Parkinson’s Disease |
| title_short | Deep Brain Stimulation Can Preserve Working Status in Parkinson’s Disease |
| title_sort | deep brain stimulation can preserve working status in parkinson s disease |
| url | http://dx.doi.org/10.1155/2015/936865 |
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