Does COVID-19 Infection Continue to Affect Self-Reported and Objective Sleep? A Longitudinal Study of Good Sleepers

Jun Wu,1– 3 Baixin Chen,1– 3 Qingsong Qin,4 Yanyuan Dai,1– 3 Le Chen,1– 3 Dandan Zheng,1– 3 Jiansheng Zhang,1– 3 Yun Li1– 3 1Department of Sleep Medicine, Mental Health Center of Shantou University, Shantou, Guangdong, People’s Republic of China; 2Sleep Medicine Center, Shantou University Medical Co...

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Main Authors: Wu J, Chen B, Qin Q, Dai Y, Chen L, Zheng D, Zhang J, Li Y
Format: Article
Language:English
Published: Dove Medical Press 2025-06-01
Series:Nature and Science of Sleep
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Online Access:https://www.dovepress.com/does-covid-19-infection-continue-to-affect-self-reported-and-objective-peer-reviewed-fulltext-article-NSS
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author Wu J
Chen B
Qin Q
Dai Y
Chen L
Zheng D
Zhang J
Li Y
author_facet Wu J
Chen B
Qin Q
Dai Y
Chen L
Zheng D
Zhang J
Li Y
author_sort Wu J
collection DOAJ
description Jun Wu,1– 3 Baixin Chen,1– 3 Qingsong Qin,4 Yanyuan Dai,1– 3 Le Chen,1– 3 Dandan Zheng,1– 3 Jiansheng Zhang,1– 3 Yun Li1– 3 1Department of Sleep Medicine, Mental Health Center of Shantou University, Shantou, Guangdong, People’s Republic of China; 2Sleep Medicine Center, Shantou University Medical College, Shantou, Guangdong, People’s Republic of China; 3Shantou University Medical College—Faculty of Medicine of University of Manitoba Joint Laboratory of Biological Psychiatry, Shantou, Guangdong, People’s Republic of China; 4Laboratory of Human Virology and Oncology, Shantou University Medical College, Shantou, People’s Republic of ChinaCorrespondence: Yun Li, Department of Sleep Medicine,Mental Health Center of Shantou University, North Taishan Road, Wanji District, Shantou, Guangdong, 515041, People’s Republic of China, Email s_liyun@stu.edu.cnBackground: Whether COVID-19 infection continues to affect both self-reported and objective sleep is not clear. This longitudinal study aims to investigate the impact of COVID-19 infection on self-reported and objective sleep of good sleepers.Methods: Fifteen good sleepers, with prior COVID infection, completed self-reported and objective sleep assessments at 3 time points: pre-COVID-19 infection, short-term post-COVID-19 infection for 1 month and long-term post-COVID-19 infection for 6 months. Self-reported sleep quality was assessed with the Pittsburgh Sleep Quality Index (PSQI). Self-reported sleep onset latency (s-SOL) and sleep efficiency (s-SE) were extracted from the PSQI. Objective sleep was assessed by overnight polysomnography. Nighttime electroencephalogram (EEG) relative power at central EEG derivations during sleep was calculated.Results: Total scores of the PSQI (P=0.003), s-SOL (P=0.017) and s-SE (P=0.040) changed across the 3 time points. Specifically, total PSQI scores (P=0.002) and s-SOL (P=0.011) increased, while s-SE decreased (P=0.019) from the pre-COVID-19 infected period to the short-term post-COVID-19 infected period. However, there were no significant differences regarding PSQI scores, s-SOL or s-SE between short-term and long-term post-COVID-19 infected periods, or between pre-COVID-19 and long-term post-COVID-19 infected periods (all P> 0.999). The changes in objective sleep were not significant across different periods except shorter o-SOL at the long-term post-COVID-19 infected period compared to the pre-COVID-19 (P=0.028) and short-term post-COVID-19 infected periods (P=0.010). Similarly, the changes in EEG relative power were not significant across different periods except the relative alpha EEG power during REM sleep (P=0.007).Conclusion: COVID-19 infection has temporary adverse effect on self-reported sleep but no effect on objective sleep of good sleepers.Keywords: COVID-19 infection, self-reported sleep, objective sleep
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spelling doaj-art-3d94973afa104f89b74d79a9558206552025-08-20T02:24:08ZengDove Medical PressNature and Science of Sleep1179-16082025-06-01Volume 17Issue 114211430104051Does COVID-19 Infection Continue to Affect Self-Reported and Objective Sleep? A Longitudinal Study of Good SleepersWu J0Chen BQin Q1Dai Y2Chen LZheng DZhang J3Li Y4sleep medicine centerLaboratory of Human Virology and OncologySleep medicine centerDepartment of Sleep Medicinesleep medicine centerJun Wu,1– 3 Baixin Chen,1– 3 Qingsong Qin,4 Yanyuan Dai,1– 3 Le Chen,1– 3 Dandan Zheng,1– 3 Jiansheng Zhang,1– 3 Yun Li1– 3 1Department of Sleep Medicine, Mental Health Center of Shantou University, Shantou, Guangdong, People’s Republic of China; 2Sleep Medicine Center, Shantou University Medical College, Shantou, Guangdong, People’s Republic of China; 3Shantou University Medical College—Faculty of Medicine of University of Manitoba Joint Laboratory of Biological Psychiatry, Shantou, Guangdong, People’s Republic of China; 4Laboratory of Human Virology and Oncology, Shantou University Medical College, Shantou, People’s Republic of ChinaCorrespondence: Yun Li, Department of Sleep Medicine,Mental Health Center of Shantou University, North Taishan Road, Wanji District, Shantou, Guangdong, 515041, People’s Republic of China, Email s_liyun@stu.edu.cnBackground: Whether COVID-19 infection continues to affect both self-reported and objective sleep is not clear. This longitudinal study aims to investigate the impact of COVID-19 infection on self-reported and objective sleep of good sleepers.Methods: Fifteen good sleepers, with prior COVID infection, completed self-reported and objective sleep assessments at 3 time points: pre-COVID-19 infection, short-term post-COVID-19 infection for 1 month and long-term post-COVID-19 infection for 6 months. Self-reported sleep quality was assessed with the Pittsburgh Sleep Quality Index (PSQI). Self-reported sleep onset latency (s-SOL) and sleep efficiency (s-SE) were extracted from the PSQI. Objective sleep was assessed by overnight polysomnography. Nighttime electroencephalogram (EEG) relative power at central EEG derivations during sleep was calculated.Results: Total scores of the PSQI (P=0.003), s-SOL (P=0.017) and s-SE (P=0.040) changed across the 3 time points. Specifically, total PSQI scores (P=0.002) and s-SOL (P=0.011) increased, while s-SE decreased (P=0.019) from the pre-COVID-19 infected period to the short-term post-COVID-19 infected period. However, there were no significant differences regarding PSQI scores, s-SOL or s-SE between short-term and long-term post-COVID-19 infected periods, or between pre-COVID-19 and long-term post-COVID-19 infected periods (all P> 0.999). The changes in objective sleep were not significant across different periods except shorter o-SOL at the long-term post-COVID-19 infected period compared to the pre-COVID-19 (P=0.028) and short-term post-COVID-19 infected periods (P=0.010). Similarly, the changes in EEG relative power were not significant across different periods except the relative alpha EEG power during REM sleep (P=0.007).Conclusion: COVID-19 infection has temporary adverse effect on self-reported sleep but no effect on objective sleep of good sleepers.Keywords: COVID-19 infection, self-reported sleep, objective sleephttps://www.dovepress.com/does-covid-19-infection-continue-to-affect-self-reported-and-objective-peer-reviewed-fulltext-article-NSSCOVID-19 infectionSelf-reported sleepObjective sleep
spellingShingle Wu J
Chen B
Qin Q
Dai Y
Chen L
Zheng D
Zhang J
Li Y
Does COVID-19 Infection Continue to Affect Self-Reported and Objective Sleep? A Longitudinal Study of Good Sleepers
Nature and Science of Sleep
COVID-19 infection
Self-reported sleep
Objective sleep
title Does COVID-19 Infection Continue to Affect Self-Reported and Objective Sleep? A Longitudinal Study of Good Sleepers
title_full Does COVID-19 Infection Continue to Affect Self-Reported and Objective Sleep? A Longitudinal Study of Good Sleepers
title_fullStr Does COVID-19 Infection Continue to Affect Self-Reported and Objective Sleep? A Longitudinal Study of Good Sleepers
title_full_unstemmed Does COVID-19 Infection Continue to Affect Self-Reported and Objective Sleep? A Longitudinal Study of Good Sleepers
title_short Does COVID-19 Infection Continue to Affect Self-Reported and Objective Sleep? A Longitudinal Study of Good Sleepers
title_sort does covid 19 infection continue to affect self reported and objective sleep a longitudinal study of good sleepers
topic COVID-19 infection
Self-reported sleep
Objective sleep
url https://www.dovepress.com/does-covid-19-infection-continue-to-affect-self-reported-and-objective-peer-reviewed-fulltext-article-NSS
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