Alternative therapy interaction with warfarin: what doctors should know

Warfarin effectiveness and safety is substantially affected by concurrent therapy. This paper reviews the main mechanisms of warfarin interactions with other agents, which underlie adverse effect development: platelet dysfunction, gastro-intestinal effects, suppressed intestinal synthesis of vitamin...

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Main Authors: T. B. Kozlova, T. V. Taratuta, M. B. Aksenova, T. V. Khlevchuk
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2010-06-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/2094
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author T. B. Kozlova
T. V. Taratuta
M. B. Aksenova
T. V. Khlevchuk
author_facet T. B. Kozlova
T. V. Taratuta
M. B. Aksenova
T. V. Khlevchuk
author_sort T. B. Kozlova
collection DOAJ
description Warfarin effectiveness and safety is substantially affected by concurrent therapy. This paper reviews the main mechanisms of warfarin interactions with other agents, which underlie adverse effect development: platelet dysfunction, gastro-intestinal effects, suppressed intestinal synthesis of vitamin K, disturbed warfarin metabolism, or disrupted vitamin K cycle. The main medication groups, affecting warfarin effectiveness and safety, are presented. The effects of foods, supplements, and herbal medications on anticoagulant effect of warfarin are discussed.
format Article
id doaj-art-3d8f4eaffb914e3dbfbfcff9ee84e8fd
institution Kabale University
issn 1728-8800
2619-0125
language Russian
publishDate 2010-06-01
publisher «SILICEA-POLIGRAF» LLC
record_format Article
series Кардиоваскулярная терапия и профилактика
spelling doaj-art-3d8f4eaffb914e3dbfbfcff9ee84e8fd2025-08-20T03:57:09Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252010-06-01931061101805Alternative therapy interaction with warfarin: what doctors should knowT. B. Kozlova0T. V. Taratuta1M. B. Aksenova2T. V. Khlevchuk3I.M. Sechenov Moscow Medical Academy. MoscowI.M. Sechenov Moscow Medical Academy. MoscowI.M. Sechenov Moscow Medical Academy. MoscowI.M. Sechenov Moscow Medical Academy. MoscowWarfarin effectiveness and safety is substantially affected by concurrent therapy. This paper reviews the main mechanisms of warfarin interactions with other agents, which underlie adverse effect development: platelet dysfunction, gastro-intestinal effects, suppressed intestinal synthesis of vitamin K, disturbed warfarin metabolism, or disrupted vitamin K cycle. The main medication groups, affecting warfarin effectiveness and safety, are presented. The effects of foods, supplements, and herbal medications on anticoagulant effect of warfarin are discussed.https://cardiovascular.elpub.ru/jour/article/view/2094warfarinconcurrent therapyinteraction with foods and herbal medicationsinr control
spellingShingle T. B. Kozlova
T. V. Taratuta
M. B. Aksenova
T. V. Khlevchuk
Alternative therapy interaction with warfarin: what doctors should know
Кардиоваскулярная терапия и профилактика
warfarin
concurrent therapy
interaction with foods and herbal medications
inr control
title Alternative therapy interaction with warfarin: what doctors should know
title_full Alternative therapy interaction with warfarin: what doctors should know
title_fullStr Alternative therapy interaction with warfarin: what doctors should know
title_full_unstemmed Alternative therapy interaction with warfarin: what doctors should know
title_short Alternative therapy interaction with warfarin: what doctors should know
title_sort alternative therapy interaction with warfarin what doctors should know
topic warfarin
concurrent therapy
interaction with foods and herbal medications
inr control
url https://cardiovascular.elpub.ru/jour/article/view/2094
work_keys_str_mv AT tbkozlova alternativetherapyinteractionwithwarfarinwhatdoctorsshouldknow
AT tvtaratuta alternativetherapyinteractionwithwarfarinwhatdoctorsshouldknow
AT mbaksenova alternativetherapyinteractionwithwarfarinwhatdoctorsshouldknow
AT tvkhlevchuk alternativetherapyinteractionwithwarfarinwhatdoctorsshouldknow