Pleomorphic Invasive Ductal Carcinoma of the Breast in a Patient with Huntington’s Disease

A pleomorphic invasive ductal carcinoma developed in a patient with Huntington’s disease. The tumour showed marked nuclear pleomorphism and contained large number of bizarre tumour giant cells and abundant abnormal mitoses. Tumour cells showed nuclear vesicles and inclusions similar to those describ...

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Main Author: Sami Shousha
Format: Article
Language:English
Published: Wiley 2014-01-01
Series:Case Reports in Pathology
Online Access:http://dx.doi.org/10.1155/2014/979137
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author Sami Shousha
author_facet Sami Shousha
author_sort Sami Shousha
collection DOAJ
description A pleomorphic invasive ductal carcinoma developed in a patient with Huntington’s disease. The tumour showed marked nuclear pleomorphism and contained large number of bizarre tumour giant cells and abundant abnormal mitoses. Tumour cells showed nuclear vesicles and inclusions similar to those described in nuclei of neural cells in patients with Huntington’s disease. The case suggests that, in some patients, tumour morphology may reflect specific individual features.
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series Case Reports in Pathology
spelling doaj-art-3d863a48e14c41f6b613add94d3bc6c42025-08-20T03:35:51ZengWileyCase Reports in Pathology2090-67812090-679X2014-01-01201410.1155/2014/979137979137Pleomorphic Invasive Ductal Carcinoma of the Breast in a Patient with Huntington’s DiseaseSami Shousha0Department of Histopathology, Imperial College Healthcare NHS Trust and Imperial College, Charing Cross Hospital, Fulham Palace Road, London W6 8RF, UKA pleomorphic invasive ductal carcinoma developed in a patient with Huntington’s disease. The tumour showed marked nuclear pleomorphism and contained large number of bizarre tumour giant cells and abundant abnormal mitoses. Tumour cells showed nuclear vesicles and inclusions similar to those described in nuclei of neural cells in patients with Huntington’s disease. The case suggests that, in some patients, tumour morphology may reflect specific individual features.http://dx.doi.org/10.1155/2014/979137
spellingShingle Sami Shousha
Pleomorphic Invasive Ductal Carcinoma of the Breast in a Patient with Huntington’s Disease
Case Reports in Pathology
title Pleomorphic Invasive Ductal Carcinoma of the Breast in a Patient with Huntington’s Disease
title_full Pleomorphic Invasive Ductal Carcinoma of the Breast in a Patient with Huntington’s Disease
title_fullStr Pleomorphic Invasive Ductal Carcinoma of the Breast in a Patient with Huntington’s Disease
title_full_unstemmed Pleomorphic Invasive Ductal Carcinoma of the Breast in a Patient with Huntington’s Disease
title_short Pleomorphic Invasive Ductal Carcinoma of the Breast in a Patient with Huntington’s Disease
title_sort pleomorphic invasive ductal carcinoma of the breast in a patient with huntington s disease
url http://dx.doi.org/10.1155/2014/979137
work_keys_str_mv AT samishousha pleomorphicinvasiveductalcarcinomaofthebreastinapatientwithhuntingtonsdisease