CTRP3 attenuates myocardial lipotoxicity via suppression of lipid accumulation, inflammation, apoptosis, and mitochondrial oxidative stress

CTRP3 attenuates myocardial lipotoxicity via suppression of lipid accumulation, inflammation, apoptosis, and mitochondrial oxidative stress

Myocardial lipotoxicity, a pathophysiological condition characterized by cardiomyocyte damage resulting from dysregulated fatty acid metabolism, plays a pivotal role in cardiovascular disease progression. C1q/tumor necrosis factor-related protein-3 (CTRP3), a novel adipocytokine with pleiotropic met...

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Bibliographic Details
Main Authors:	Qingpeng Wang, Jiangyang Chi, Chen Wang, Yanhong Yuan, Rui Tian, Yun Yang, Xinzhong Chen
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2025-05-01
Series:	Frontiers in Cardiovascular Medicine
Subjects:	CTRP3 myocardial lipotoxicity lipid metabolism inflammation oxidative stress
Online Access:	https://www.frontiersin.org/articles/10.3389/fcvm.2025.1575929/full
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