Recurrent Pulmonary Infection Caused by Schizophyllum commune: A Case Report and Management of Inflammation
ABSTRACT This case report documents a recurrent pulmonary infection caused by Schizophyllum commune in a 59‐year‐old woman with repeated admissions for cough and sputum production. Using mNGS on BALF, S. commune sequences were identified. The patient's clinical symptoms, lab results, and imagin...
Saved in:
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2025-07-01
|
| Series: | Respirology Case Reports |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/rcr2.70239 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849245941675065344 |
|---|---|
| author | Shuai Ren Ping Xu Manyu Dai Ruifang Chen Haicheng Tang |
| author_facet | Shuai Ren Ping Xu Manyu Dai Ruifang Chen Haicheng Tang |
| author_sort | Shuai Ren |
| collection | DOAJ |
| description | ABSTRACT This case report documents a recurrent pulmonary infection caused by Schizophyllum commune in a 59‐year‐old woman with repeated admissions for cough and sputum production. Using mNGS on BALF, S. commune sequences were identified. The patient's clinical symptoms, lab results, and imaging features aligned with six criteria from Asano's assessment table, confirming ABPM. During treatment, bronchoscopic airway clearance, antifungal agents, and inhaled corticosteroids proved effective. The case highlights mNGS's role in diagnosing rare fungal infections and the need for individualised antifungal therapy. Azithromycin's potential anti‐inflammatory effects were noted, though its specific application in ABPM requires further study. Caution is advised in future use, with more research needed on its mechanism in such cases. |
| format | Article |
| id | doaj-art-3d69a1c15fae4e9bb86e5a8ad09bd130 |
| institution | Kabale University |
| issn | 2051-3380 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | Wiley |
| record_format | Article |
| series | Respirology Case Reports |
| spelling | doaj-art-3d69a1c15fae4e9bb86e5a8ad09bd1302025-08-20T03:58:40ZengWileyRespirology Case Reports2051-33802025-07-01137n/an/a10.1002/rcr2.70239Recurrent Pulmonary Infection Caused by Schizophyllum commune: A Case Report and Management of InflammationShuai Ren0Ping Xu1Manyu Dai2Ruifang Chen3Haicheng Tang4Department of Pulmonology Shanghai Public Health Clinical Center Shanghai ChinaDepartment of Pulmonology Shanghai Public Health Clinical Center Shanghai ChinaDepartment of Cardiology The Second Affiliated Hospital of Bengbu Medical College Bengbu ChinaDepartment of Pulmonology Shanghai Public Health Clinical Center Shanghai ChinaDepartment of Pulmonology Shanghai Public Health Clinical Center Shanghai ChinaABSTRACT This case report documents a recurrent pulmonary infection caused by Schizophyllum commune in a 59‐year‐old woman with repeated admissions for cough and sputum production. Using mNGS on BALF, S. commune sequences were identified. The patient's clinical symptoms, lab results, and imaging features aligned with six criteria from Asano's assessment table, confirming ABPM. During treatment, bronchoscopic airway clearance, antifungal agents, and inhaled corticosteroids proved effective. The case highlights mNGS's role in diagnosing rare fungal infections and the need for individualised antifungal therapy. Azithromycin's potential anti‐inflammatory effects were noted, though its specific application in ABPM requires further study. Caution is advised in future use, with more research needed on its mechanism in such cases.https://doi.org/10.1002/rcr2.70239airway clearanceallergic bronchopulmonary mycosisazithromycinglucocorticoidsSchizophyllum communevoriconazole |
| spellingShingle | Shuai Ren Ping Xu Manyu Dai Ruifang Chen Haicheng Tang Recurrent Pulmonary Infection Caused by Schizophyllum commune: A Case Report and Management of Inflammation Respirology Case Reports airway clearance allergic bronchopulmonary mycosis azithromycin glucocorticoids Schizophyllum commune voriconazole |
| title | Recurrent Pulmonary Infection Caused by Schizophyllum commune: A Case Report and Management of Inflammation |
| title_full | Recurrent Pulmonary Infection Caused by Schizophyllum commune: A Case Report and Management of Inflammation |
| title_fullStr | Recurrent Pulmonary Infection Caused by Schizophyllum commune: A Case Report and Management of Inflammation |
| title_full_unstemmed | Recurrent Pulmonary Infection Caused by Schizophyllum commune: A Case Report and Management of Inflammation |
| title_short | Recurrent Pulmonary Infection Caused by Schizophyllum commune: A Case Report and Management of Inflammation |
| title_sort | recurrent pulmonary infection caused by schizophyllum commune a case report and management of inflammation |
| topic | airway clearance allergic bronchopulmonary mycosis azithromycin glucocorticoids Schizophyllum commune voriconazole |
| url | https://doi.org/10.1002/rcr2.70239 |
| work_keys_str_mv | AT shuairen recurrentpulmonaryinfectioncausedbyschizophyllumcommuneacasereportandmanagementofinflammation AT pingxu recurrentpulmonaryinfectioncausedbyschizophyllumcommuneacasereportandmanagementofinflammation AT manyudai recurrentpulmonaryinfectioncausedbyschizophyllumcommuneacasereportandmanagementofinflammation AT ruifangchen recurrentpulmonaryinfectioncausedbyschizophyllumcommuneacasereportandmanagementofinflammation AT haichengtang recurrentpulmonaryinfectioncausedbyschizophyllumcommuneacasereportandmanagementofinflammation |