Case Report: Severe ophiasis-pattern alopecia areata with concomitant atopic dermatitis in a 5-year-old boy successfully treated with dupilumab

Alopecia areata (AA) is the third most common reason for dermatological consultations among children. Despite the availability of numerous therapies for AA, including topical and systemic modalities, management options for children diagnosed with severe AA are limited due to the lack of safe and eff...

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Main Authors: Zhendong Wei, Chao Yu, Aoxue Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Pediatrics
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2025.1517769/full
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author Zhendong Wei
Chao Yu
Aoxue Wang
author_facet Zhendong Wei
Chao Yu
Aoxue Wang
author_sort Zhendong Wei
collection DOAJ
description Alopecia areata (AA) is the third most common reason for dermatological consultations among children. Despite the availability of numerous therapies for AA, including topical and systemic modalities, management options for children diagnosed with severe AA are limited due to the lack of safe and effective treatments suitable for long-term use. Herein, a case involving a 5-year-old boy with severe ophiasis-pattern AA and moderate atopic dermatitis (AD), who was successfully treated with dupilumab, is reported.
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institution Kabale University
issn 2296-2360
language English
publishDate 2025-02-01
publisher Frontiers Media S.A.
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series Frontiers in Pediatrics
spelling doaj-art-3d6101f83b2644b99e40f9c15c6e72612025-02-10T05:16:11ZengFrontiers Media S.A.Frontiers in Pediatrics2296-23602025-02-011310.3389/fped.2025.15177691517769Case Report: Severe ophiasis-pattern alopecia areata with concomitant atopic dermatitis in a 5-year-old boy successfully treated with dupilumabZhendong WeiChao YuAoxue WangAlopecia areata (AA) is the third most common reason for dermatological consultations among children. Despite the availability of numerous therapies for AA, including topical and systemic modalities, management options for children diagnosed with severe AA are limited due to the lack of safe and effective treatments suitable for long-term use. Herein, a case involving a 5-year-old boy with severe ophiasis-pattern AA and moderate atopic dermatitis (AD), who was successfully treated with dupilumab, is reported.https://www.frontiersin.org/articles/10.3389/fped.2025.1517769/fullalopecia areataophiasis-pattern alopecia areataatopic dermatitispediatric patientsTh2 signalingdupilumab
spellingShingle Zhendong Wei
Chao Yu
Aoxue Wang
Case Report: Severe ophiasis-pattern alopecia areata with concomitant atopic dermatitis in a 5-year-old boy successfully treated with dupilumab
Frontiers in Pediatrics
alopecia areata
ophiasis-pattern alopecia areata
atopic dermatitis
pediatric patients
Th2 signaling
dupilumab
title Case Report: Severe ophiasis-pattern alopecia areata with concomitant atopic dermatitis in a 5-year-old boy successfully treated with dupilumab
title_full Case Report: Severe ophiasis-pattern alopecia areata with concomitant atopic dermatitis in a 5-year-old boy successfully treated with dupilumab
title_fullStr Case Report: Severe ophiasis-pattern alopecia areata with concomitant atopic dermatitis in a 5-year-old boy successfully treated with dupilumab
title_full_unstemmed Case Report: Severe ophiasis-pattern alopecia areata with concomitant atopic dermatitis in a 5-year-old boy successfully treated with dupilumab
title_short Case Report: Severe ophiasis-pattern alopecia areata with concomitant atopic dermatitis in a 5-year-old boy successfully treated with dupilumab
title_sort case report severe ophiasis pattern alopecia areata with concomitant atopic dermatitis in a 5 year old boy successfully treated with dupilumab
topic alopecia areata
ophiasis-pattern alopecia areata
atopic dermatitis
pediatric patients
Th2 signaling
dupilumab
url https://www.frontiersin.org/articles/10.3389/fped.2025.1517769/full
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AT chaoyu casereportsevereophiasispatternalopeciaareatawithconcomitantatopicdermatitisina5yearoldboysuccessfullytreatedwithdupilumab
AT aoxuewang casereportsevereophiasispatternalopeciaareatawithconcomitantatopicdermatitisina5yearoldboysuccessfullytreatedwithdupilumab