A simple analysis of vaccination strategies for rubella
We consider an SEIR epidemic model with vertical transmission introduced by Li, Smith and Wang, [23], and apply optimal control theory to assess the effects of vaccination strategies on the model dynamics. The strategy is chosen to minimize the total number of infectious individuals and the cost ass...
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Main Author: | |
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Format: | Article |
Language: | English |
Published: |
AIMS Press
2011-05-01
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Series: | Mathematical Biosciences and Engineering |
Subjects: | |
Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2011.8.677 |
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Summary: | We consider an SEIR epidemic model with vertical transmission introduced by Li, Smith and Wang, [23], and apply optimal control theory to assess the effects of vaccination strategies on the model dynamics. The strategy is chosen to minimize the total number of infectious individuals and the cost associated with vaccination. We derive the optimality system and solve it numerically. The theoretical findings are then used to simulate a vaccination campaign for rubella in China. |
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ISSN: | 1551-0018 |