Ranula as the First Symptom of HIV Infection in Young Patients

Introduction. Oral manifestations are often the earliest HIV signs. Salivary gland diseases are a common form of HIV expression. A ranula can occur in association with HIV. However, this manifestation is rarely considered as the disease sentinel sign. We present two cases of children consulting for...

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Main Authors: X. Vanden Eynden, C. Bouland, D. Dequanter, M. Gerbaux, S. Kampouridis, E. Boutremans, I. Loeb
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2021/8874662
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author X. Vanden Eynden
C. Bouland
D. Dequanter
M. Gerbaux
S. Kampouridis
E. Boutremans
I. Loeb
author_facet X. Vanden Eynden
C. Bouland
D. Dequanter
M. Gerbaux
S. Kampouridis
E. Boutremans
I. Loeb
author_sort X. Vanden Eynden
collection DOAJ
description Introduction. Oral manifestations are often the earliest HIV signs. Salivary gland diseases are a common form of HIV expression. A ranula can occur in association with HIV. However, this manifestation is rarely considered as the disease sentinel sign. We present two cases of children consulting for a ranula, leading to the diagnosis of a previously unknown HIV infection. Case Reports. Two children, respectively, 5 and 13, were treated for a ranula by marsupialization. Relapse occurred in both cases, and thereafter, a ranula excision was performed. While the follow-up was uneventful, HIV infection was diagnosed during the patients’ care. The only sign or symptom observed was the ranula. A routine HIV testing of ranula patients would have allowed earlier care. Conclusion. Routine HIV testing of patients with a ranula is justified and may be recommended, especially for children. Ranula excision associated with the sublingual gland resection is suggested in order to avoid recurrence.
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series Case Reports in Pediatrics
spelling doaj-art-3d5431127cb54d299ebc9c928406d6bc2025-02-03T05:47:39ZengWileyCase Reports in Pediatrics2090-68032090-68112021-01-01202110.1155/2021/88746628874662Ranula as the First Symptom of HIV Infection in Young PatientsX. Vanden Eynden0C. Bouland1D. Dequanter2M. Gerbaux3S. Kampouridis4E. Boutremans5I. Loeb6Department of Stomatology and Maxillofacial Surgery, Université Libre de Bruxelles (ULB), CHU-Saint-Pierre, Rue Haute 322, Brussels 1000, BelgiumDepartment of Stomatology and Maxillofacial Surgery, Université Libre de Bruxelles (ULB), CHU-Saint-Pierre, Rue Haute 322, Brussels 1000, BelgiumDepartment of Stomatology and Maxillofacial Surgery, Université Libre de Bruxelles (ULB), CHU-Saint-Pierre, Rue Haute 322, Brussels 1000, BelgiumDepartment of Pediatrics, Queen Fabiola Children’s University Hospital, Université Libre de Bruxelles (ULB), Avenue Jean-Joseph Crocq 15, Brussels 1020, BelgiumDepartment of Radiology, Université Libre de Bruxelles (ULB), CHU-Saint-Pierre, Rue Haute 322, Brussels 1000, BelgiumDepartment of Stomatology and Maxillofacial Surgery, Université Libre de Bruxelles (ULB), CHU-Saint-Pierre, Rue Haute 322, Brussels 1000, BelgiumDepartment of Stomatology and Maxillofacial Surgery, Université Libre de Bruxelles (ULB), CHU-Saint-Pierre, Rue Haute 322, Brussels 1000, BelgiumIntroduction. Oral manifestations are often the earliest HIV signs. Salivary gland diseases are a common form of HIV expression. A ranula can occur in association with HIV. However, this manifestation is rarely considered as the disease sentinel sign. We present two cases of children consulting for a ranula, leading to the diagnosis of a previously unknown HIV infection. Case Reports. Two children, respectively, 5 and 13, were treated for a ranula by marsupialization. Relapse occurred in both cases, and thereafter, a ranula excision was performed. While the follow-up was uneventful, HIV infection was diagnosed during the patients’ care. The only sign or symptom observed was the ranula. A routine HIV testing of ranula patients would have allowed earlier care. Conclusion. Routine HIV testing of patients with a ranula is justified and may be recommended, especially for children. Ranula excision associated with the sublingual gland resection is suggested in order to avoid recurrence.http://dx.doi.org/10.1155/2021/8874662
spellingShingle X. Vanden Eynden
C. Bouland
D. Dequanter
M. Gerbaux
S. Kampouridis
E. Boutremans
I. Loeb
Ranula as the First Symptom of HIV Infection in Young Patients
Case Reports in Pediatrics
title Ranula as the First Symptom of HIV Infection in Young Patients
title_full Ranula as the First Symptom of HIV Infection in Young Patients
title_fullStr Ranula as the First Symptom of HIV Infection in Young Patients
title_full_unstemmed Ranula as the First Symptom of HIV Infection in Young Patients
title_short Ranula as the First Symptom of HIV Infection in Young Patients
title_sort ranula as the first symptom of hiv infection in young patients
url http://dx.doi.org/10.1155/2021/8874662
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