Evolution of Light-Sensitive Proteins in Optogenetic Approaches for Vision Restoration: A Comprehensive Review

Evolution of Light-Sensitive Proteins in Optogenetic Approaches for Vision Restoration: A Comprehensive Review

Retinal degenerations, such as age-related macular degeneration and retinitis pigmentosa, present significant challenges due to genetic heterogeneity, limited therapeutic options, and the progressive loss of photoreceptors in advanced stages. These challenges are compounded by difficulties in precis...

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Bibliographic Details
Main Authors:	Kamil Poboży, Tomasz Poboży, Paweł Domański, Michał Derczyński, Wojciech Konarski, Julia Domańska-Poboża
Format:	Article
Language:	English
Published:	MDPI AG 2025-02-01
Series:	Biomedicines
Subjects:	retinal degeneration optogenetics opsin channelrhodopsin-2 ChrimsonR multi-characteristic opsin 1
Online Access:	https://www.mdpi.com/2227-9059/13/2/429
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