The Value of Sacral Reflex and Sympathetic Skin Reflex in the Diagnosis of Multiple System Atrophy P-Type
Objectives. To observe the characteristics of sacral reflex and sympathetic skin reflex in patients with Parkinson’s disease (PD) and multiple system atrophy P-type (MSA-P) and to analyze their value as a differential diagnostic method. Methods. The data of 30 healthy people, 58 PD patients, and 52...
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| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2021-01-01
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| Series: | Parkinson's Disease |
| Online Access: | http://dx.doi.org/10.1155/2021/6646259 |
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| author | Xiaohang Li Chengju Wang Xueming Zhang Wanli Zhang Binbin Deng Xun Wang Huanjie Huang |
| author_facet | Xiaohang Li Chengju Wang Xueming Zhang Wanli Zhang Binbin Deng Xun Wang Huanjie Huang |
| author_sort | Xiaohang Li |
| collection | DOAJ |
| description | Objectives. To observe the characteristics of sacral reflex and sympathetic skin reflex in patients with Parkinson’s disease (PD) and multiple system atrophy P-type (MSA-P) and to analyze their value as a differential diagnostic method. Methods. The data of 30 healthy people, 58 PD patients, and 52 MSA-P patients from the First Affiliated Hospital of Wenzhou Medical University were collected. Electrophysiological bulbocavernosus reflex (BCR) and sympathetic skin response (SSR) were evaluated using the Keypoint EMG/EP system. The latency period, amplitude, and extraction rate of BCR and SSR were compared between the control, PD, and MSA-P groups. Results. The incidence of the related autonomic damage in the PD group was lower than that of the MSA-P group. For BCR, the latency period was shorter and the amplitude and elicitation rates were lower in the PD group than in the MSA-P group. For SSR, the latency period was longer in the MSA-P and PD groups than in the control group, but the difference was not statistically significant. Conclusion. SSR cannot be used to assess autonomic nerve function. PD patients can have clinical symptoms similar to those of MSA-P patients, but the incidence is lower. Both MSA-P and PD patients have a damage to the BCR arc, but the MSA-P patients have a more severe damage. |
| format | Article |
| id | doaj-art-3d3f9b1978054adaa1c2effbf656d20b |
| institution | Kabale University |
| issn | 2090-8083 2042-0080 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Parkinson's Disease |
| spelling | doaj-art-3d3f9b1978054adaa1c2effbf656d20b2025-08-20T03:55:33ZengWileyParkinson's Disease2090-80832042-00802021-01-01202110.1155/2021/66462596646259The Value of Sacral Reflex and Sympathetic Skin Reflex in the Diagnosis of Multiple System Atrophy P-TypeXiaohang Li0Chengju Wang1Xueming Zhang2Wanli Zhang3Binbin Deng4Xun Wang5Huanjie Huang6Yanzhou Branch of Affiliated Hospital of Jining Medical University, Jining 272100, ChinaDepartment of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, ChinaThe First People’s Hospital of Ningyang County, Taian 271000, ChinaDepartment of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, ChinaDepartment of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, ChinaDepartment of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, ChinaDepartment of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, ChinaObjectives. To observe the characteristics of sacral reflex and sympathetic skin reflex in patients with Parkinson’s disease (PD) and multiple system atrophy P-type (MSA-P) and to analyze their value as a differential diagnostic method. Methods. The data of 30 healthy people, 58 PD patients, and 52 MSA-P patients from the First Affiliated Hospital of Wenzhou Medical University were collected. Electrophysiological bulbocavernosus reflex (BCR) and sympathetic skin response (SSR) were evaluated using the Keypoint EMG/EP system. The latency period, amplitude, and extraction rate of BCR and SSR were compared between the control, PD, and MSA-P groups. Results. The incidence of the related autonomic damage in the PD group was lower than that of the MSA-P group. For BCR, the latency period was shorter and the amplitude and elicitation rates were lower in the PD group than in the MSA-P group. For SSR, the latency period was longer in the MSA-P and PD groups than in the control group, but the difference was not statistically significant. Conclusion. SSR cannot be used to assess autonomic nerve function. PD patients can have clinical symptoms similar to those of MSA-P patients, but the incidence is lower. Both MSA-P and PD patients have a damage to the BCR arc, but the MSA-P patients have a more severe damage.http://dx.doi.org/10.1155/2021/6646259 |
| spellingShingle | Xiaohang Li Chengju Wang Xueming Zhang Wanli Zhang Binbin Deng Xun Wang Huanjie Huang The Value of Sacral Reflex and Sympathetic Skin Reflex in the Diagnosis of Multiple System Atrophy P-Type Parkinson's Disease |
| title | The Value of Sacral Reflex and Sympathetic Skin Reflex in the Diagnosis of Multiple System Atrophy P-Type |
| title_full | The Value of Sacral Reflex and Sympathetic Skin Reflex in the Diagnosis of Multiple System Atrophy P-Type |
| title_fullStr | The Value of Sacral Reflex and Sympathetic Skin Reflex in the Diagnosis of Multiple System Atrophy P-Type |
| title_full_unstemmed | The Value of Sacral Reflex and Sympathetic Skin Reflex in the Diagnosis of Multiple System Atrophy P-Type |
| title_short | The Value of Sacral Reflex and Sympathetic Skin Reflex in the Diagnosis of Multiple System Atrophy P-Type |
| title_sort | value of sacral reflex and sympathetic skin reflex in the diagnosis of multiple system atrophy p type |
| url | http://dx.doi.org/10.1155/2021/6646259 |
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