Drug-Induced Atrial Fibrillation / Atrial Flutter
Drug-induced atrial fibrillation / flutter (DIAF) is a serious and potentially life-threatening complication of pharmacotherapy. Purpose of the work: systematization and analysis of scientific literature data on drugs, the use of which can cause the development of DIAF, as well as on epidemiology, p...
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| Format: | Article |
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Столичная издательская компания
2022-01-01
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| Series: | Рациональная фармакотерапия в кардиологии |
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| Online Access: | https://www.rpcardio.online/jour/article/view/2636 |
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| author | O. D Ostroumova M. S. Chernyaeva A. I. Kochetkov A. E. Vorobieva D. I. Bakhteeva S. P. Korchagina O. V. Bondarets N. D. Boyko D. A. Sychev |
| author_facet | O. D Ostroumova M. S. Chernyaeva A. I. Kochetkov A. E. Vorobieva D. I. Bakhteeva S. P. Korchagina O. V. Bondarets N. D. Boyko D. A. Sychev |
| author_sort | O. D Ostroumova |
| collection | DOAJ |
| description | Drug-induced atrial fibrillation / flutter (DIAF) is a serious and potentially life-threatening complication of pharmacotherapy. Purpose of the work: systematization and analysis of scientific literature data on drugs, the use of which can cause the development of DIAF, as well as on epidemiology, pathophysiological mechanisms, risk factors, clinical picture, diagnosis and differential diagnosis, treatment and prevention of DIAF. Analysis of the literature has shown that many groups of drugs can cause the development of DIAF, with a greater frequency while taking anticancer drugs, drugs for the treatment of the cardiovascular, bronchopulmonary and central nervous systems. The mechanisms and main risk factors for the development of DIAF have not been finally established and are known only for certain drugs, therefore, this section requires further study. The main symptoms of DIAF are due to the severity of tachycardia and their influence on the parameters of central hemodynamics. For diagnosis, it is necessary to conduct an electrocardiogram (ECG) and Holter monitoring of an ECG and echocardiography. Differential diagnosis should be made with AF, which may be caused by other causes, as well as other rhythm and conduction disturbances. Successful treatment of DIAF is based on the principle of rapid recognition and immediate discontinuation of drugs (if possible), the use of which potentially caused the development of adverse drug reactions (ADR). The choice of management strategy: heart rate control or rhythm control, as well as the method of achievement (medication or non-medication), depends on the specific clinical situation. For the prevention of DIAF, it is necessary to instruct patients about possible symptoms and recommend self-monitoring of the pulse. It is important for practitioners to be wary of the risk of DIAF due to the variety of drugs that can potentially cause this ADR. |
| format | Article |
| id | doaj-art-3d3ed84853044ed2bd245ed8cf06fc44 |
| institution | Kabale University |
| issn | 1819-6446 2225-3653 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Столичная издательская компания |
| record_format | Article |
| series | Рациональная фармакотерапия в кардиологии |
| spelling | doaj-art-3d3ed84853044ed2bd245ed8cf06fc442025-08-23T10:00:34ZengСтоличная издательская компанияРациональная фармакотерапия в кардиологии1819-64462225-36532022-01-01176e1e110.20996/1819-6446-2021-12-111977Drug-Induced Atrial Fibrillation / Atrial FlutterO. D Ostroumova0M. S. Chernyaeva1A. I. Kochetkov2A. E. Vorobieva3D. I. Bakhteeva4S. P. Korchagina5O. V. Bondarets6N. D. Boyko7D. A. Sychev8Russian Medical Academy of Continuing Professional EducationCentral State Medical Academy of the Administrative Department of the President; Hospital for War Veterans No. 2Russian Medical Academy of Continuing Professional EducationMoscow State University of Medicine and Dentistry named after A.I. EvdokimovaHospital for War Veterans No. 2MedSwiss Medical CenterMoscow State University of Medicine and Dentistry named after A.I. EvdokimovaHospital for War Veterans No. 2Russian Medical Academy of Continuing Professional EducationDrug-induced atrial fibrillation / flutter (DIAF) is a serious and potentially life-threatening complication of pharmacotherapy. Purpose of the work: systematization and analysis of scientific literature data on drugs, the use of which can cause the development of DIAF, as well as on epidemiology, pathophysiological mechanisms, risk factors, clinical picture, diagnosis and differential diagnosis, treatment and prevention of DIAF. Analysis of the literature has shown that many groups of drugs can cause the development of DIAF, with a greater frequency while taking anticancer drugs, drugs for the treatment of the cardiovascular, bronchopulmonary and central nervous systems. The mechanisms and main risk factors for the development of DIAF have not been finally established and are known only for certain drugs, therefore, this section requires further study. The main symptoms of DIAF are due to the severity of tachycardia and their influence on the parameters of central hemodynamics. For diagnosis, it is necessary to conduct an electrocardiogram (ECG) and Holter monitoring of an ECG and echocardiography. Differential diagnosis should be made with AF, which may be caused by other causes, as well as other rhythm and conduction disturbances. Successful treatment of DIAF is based on the principle of rapid recognition and immediate discontinuation of drugs (if possible), the use of which potentially caused the development of adverse drug reactions (ADR). The choice of management strategy: heart rate control or rhythm control, as well as the method of achievement (medication or non-medication), depends on the specific clinical situation. For the prevention of DIAF, it is necessary to instruct patients about possible symptoms and recommend self-monitoring of the pulse. It is important for practitioners to be wary of the risk of DIAF due to the variety of drugs that can potentially cause this ADR.https://www.rpcardio.online/jour/article/view/2636drug-induced atrial fibrillationadverse drug reactionsanticancer drugsbisphosphonatesglucocorticoidsnonsteroidal anti-inflammatory drugsimmunosuppressantslocal anestheticsanabolic steroidsnicotine |
| spellingShingle | O. D Ostroumova M. S. Chernyaeva A. I. Kochetkov A. E. Vorobieva D. I. Bakhteeva S. P. Korchagina O. V. Bondarets N. D. Boyko D. A. Sychev Drug-Induced Atrial Fibrillation / Atrial Flutter Рациональная фармакотерапия в кардиологии drug-induced atrial fibrillation adverse drug reactions anticancer drugs bisphosphonates glucocorticoids nonsteroidal anti-inflammatory drugs immunosuppressants local anesthetics anabolic steroids nicotine |
| title | Drug-Induced Atrial Fibrillation / Atrial Flutter |
| title_full | Drug-Induced Atrial Fibrillation / Atrial Flutter |
| title_fullStr | Drug-Induced Atrial Fibrillation / Atrial Flutter |
| title_full_unstemmed | Drug-Induced Atrial Fibrillation / Atrial Flutter |
| title_short | Drug-Induced Atrial Fibrillation / Atrial Flutter |
| title_sort | drug induced atrial fibrillation atrial flutter |
| topic | drug-induced atrial fibrillation adverse drug reactions anticancer drugs bisphosphonates glucocorticoids nonsteroidal anti-inflammatory drugs immunosuppressants local anesthetics anabolic steroids nicotine |
| url | https://www.rpcardio.online/jour/article/view/2636 |
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