Kinetics and Mechanism of the Hydrolysis of Benzylidene Benzoylhyd - Razone Derivatives

The kinetics and mechanism of hydrolysis of a series of substituted benzylidene benzoylhydrazones (X — BBH) have been studied at five different temperatures in the range 25 — 45°c by U. V. -visible spectrophotometry. The hydrolysis reactions were found to follow first - order kinetics. A mechanism h...

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Main Authors: Maher Abu-Eid, Foad M. Mahmoud, Bassem F. Shraydeh
Format: Article
Language:English
Published: An-Najah National University 1989-09-01
Series:مجلة جامعة النجاح للأبحاث العلوم الطبيعية
Online Access:https://journals.najah.edu/media/journals/full_texts/kinetics-and-mechanism-hydrolysis-benzylidene-benzoylhyd-razone-derivatives.pdf
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author Maher Abu-Eid
Foad M. Mahmoud
Bassem F. Shraydeh
author_facet Maher Abu-Eid
Foad M. Mahmoud
Bassem F. Shraydeh
author_sort Maher Abu-Eid
collection DOAJ
description The kinetics and mechanism of hydrolysis of a series of substituted benzylidene benzoylhydrazones (X — BBH) have been studied at five different temperatures in the range 25 — 45°c by U. V. -visible spectrophotometry. The hydrolysis reactions were found to follow first - order kinetics. A mechanism has been postulated in which the attack of water on the protonated substrate is subject to general base catalysis. This mechanism has been supported by the effect of anion concentration of buffer, at constant pH, on the observed rate constant. The Bronsted ?-value for the hydrolysis reaction is 0.73. Hammett correlations, Arrhenius and thermodynamic parameters have been evaluated and discussed. The pKa values for the conjugate acids for benzylidene benzoylhydrazones derivatives (X - BBH) have been determined.
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institution Kabale University
issn 1727-2114
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language English
publishDate 1989-09-01
publisher An-Najah National University
record_format Article
series مجلة جامعة النجاح للأبحاث العلوم الطبيعية
spelling doaj-art-3d3292bee9a1447a842f76c41cee1b7e2025-08-20T03:44:04ZengAn-Najah National Universityمجلة جامعة النجاح للأبحاث العلوم الطبيعية1727-21142311-88651989-09-0161233310.35552/anujr.a.6.1.438Kinetics and Mechanism of the Hydrolysis of Benzylidene Benzoylhyd - Razone DerivativesMaher Abu-Eid0Foad M. Mahmoud1Bassem F. Shraydeh2NoneNoneNoneThe kinetics and mechanism of hydrolysis of a series of substituted benzylidene benzoylhydrazones (X — BBH) have been studied at five different temperatures in the range 25 — 45°c by U. V. -visible spectrophotometry. The hydrolysis reactions were found to follow first - order kinetics. A mechanism has been postulated in which the attack of water on the protonated substrate is subject to general base catalysis. This mechanism has been supported by the effect of anion concentration of buffer, at constant pH, on the observed rate constant. The Bronsted ?-value for the hydrolysis reaction is 0.73. Hammett correlations, Arrhenius and thermodynamic parameters have been evaluated and discussed. The pKa values for the conjugate acids for benzylidene benzoylhydrazones derivatives (X - BBH) have been determined.https://journals.najah.edu/media/journals/full_texts/kinetics-and-mechanism-hydrolysis-benzylidene-benzoylhyd-razone-derivatives.pdf
spellingShingle Maher Abu-Eid
Foad M. Mahmoud
Bassem F. Shraydeh
Kinetics and Mechanism of the Hydrolysis of Benzylidene Benzoylhyd - Razone Derivatives
مجلة جامعة النجاح للأبحاث العلوم الطبيعية
title Kinetics and Mechanism of the Hydrolysis of Benzylidene Benzoylhyd - Razone Derivatives
title_full Kinetics and Mechanism of the Hydrolysis of Benzylidene Benzoylhyd - Razone Derivatives
title_fullStr Kinetics and Mechanism of the Hydrolysis of Benzylidene Benzoylhyd - Razone Derivatives
title_full_unstemmed Kinetics and Mechanism of the Hydrolysis of Benzylidene Benzoylhyd - Razone Derivatives
title_short Kinetics and Mechanism of the Hydrolysis of Benzylidene Benzoylhyd - Razone Derivatives
title_sort kinetics and mechanism of the hydrolysis of benzylidene benzoylhyd razone derivatives
url https://journals.najah.edu/media/journals/full_texts/kinetics-and-mechanism-hydrolysis-benzylidene-benzoylhyd-razone-derivatives.pdf
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AT foadmmahmoud kineticsandmechanismofthehydrolysisofbenzylidenebenzoylhydrazonederivatives
AT bassemfshraydeh kineticsandmechanismofthehydrolysisofbenzylidenebenzoylhydrazonederivatives