Up-regulation of long non-coding RNA H19 ameliorates renal tubulointerstitial fibrosis by reducing lipid deposition and inflammatory response through regulation of the microRNA-130a-3p/long-chain acyl-CoA synthetase 1 axis

Up-regulation of long non-coding RNA H19 ameliorates renal tubulointerstitial fibrosis by reducing lipid deposition and inflammatory response through regulation of the microRNA-130a-3p/long-chain acyl-CoA synthetase 1 axis

Long non-coding RNA (lncRNA) H19 is an extensively studied lncRNA that is related to numerous pathological changes. Our previous findings have documented that serum lncRNA H19 levels are decreased in patients with chronic kidney disorder and lncRNA H19 reduction is closely correlated with renal tubu...

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Bibliographic Details
Main Authors: Yali Jiang, Feng Ma, Jing Wang, Xiaojing Chen, Lu Xue, Xinping Chen, Jinping Hu
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-12-01
Series:Non-coding RNA Research
Subjects:
Long-chain acyl-CoA synthetase 1
lncRNA H19
Lipid metabolism
microRNA-130a-3p
Renal tubulointerstitial fibrosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2468054024000891
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