Tissue gene expression analysis approach in a context of high technical and biological heterogeneity

Tissue gene expression analysis approach in a context of high technical and biological heterogeneity

Abstract Background Immune expression profiling in colorectal lesions may provide insights into the origins of antitumor immunity and senescence. Optimal approaches for analyzing samples with lower quality RNA from molecularly diverse lesions are lacking. Therefore, we developed a NanoString nCounte...

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Bibliographic Details
Main Authors: Evan Bagley, Souvik Seal, Lauren R. Fanning, Jean-Sebastien Anoma, Tami Crawford, Benjamin G. Vincent, Elizabeth L. Barry, Martha J. Shrubsole, Erin Kirk, John A. Baron, Dale C. Snover, David N. Lewin, Todd A. Mackenzie, Xiaohua Gao, Melissa A. Troester, Alexander V. Alekseyenko, Kristin Wallace
Format: Article
Language:English
Published: BMC 2025-07-01
Series:BMC Research Notes
Subjects:
Immune expression
NanoString
Sessile serrated lesion
RUV
Online Access:https://doi.org/10.1186/s13104-025-07383-0
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