Predictive modelling methods of hospital readmission risks for patients with chronic obstructive pulmonary disease (COPD): a systematic review protocol

Introduction Chronic obstructive pulmonary disease (COPD) is a significant chronic respiratory condition characterised by persistent airway obstruction, leading to substantial morbidity and mortality worldwide. Patients with COPD frequently experience hospital readmissions shortly after discharge, m...

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Main Authors: Maude Laberge, Paolo Landa, André Côté, Balkissa Tonde, Metogara Mohamed Traore
Format: Article
Language:English
Published: BMJ Publishing Group 2025-04-01
Series:BMJ Open
Online Access:https://bmjopen.bmj.com/content/15/4/e093771.full
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author Maude Laberge
Paolo Landa
André Côté
Balkissa Tonde
Metogara Mohamed Traore
author_facet Maude Laberge
Paolo Landa
André Côté
Balkissa Tonde
Metogara Mohamed Traore
author_sort Maude Laberge
collection DOAJ
description Introduction Chronic obstructive pulmonary disease (COPD) is a significant chronic respiratory condition characterised by persistent airway obstruction, leading to substantial morbidity and mortality worldwide. Patients with COPD frequently experience hospital readmissions shortly after discharge, mainly due to acute exacerbations. This review aims to identify and synthesise the reported performance metrics and methodological limitations of different predictive modelling methods for hospital readmissions in COPD patients.Method and analysis This protocol adheres to the Preferred Reporting Items for Systematic reviews and Meta-Analysis Protocols (PRISMA-P) guidelines. The review will include studies that develop or validate predictive models for hospital readmissions in COPD patients. A comprehensive search will be conducted across PubMed, Embase, Cochrane Library, IEEE Xplore, Web of Science and Google Scholar using predefined keywords. Eligible studies will include those utilising any predictive modelling method, focusing on unplanned readmissions within specified timeframes (30, 60 or 90 days). Two independent reviewers will screen titles, abstracts and full texts, selecting studies based on predefined inclusion criteria.Data extraction will be conducted based on the CHecklist for critical Appraisal and data extraction for systematic Reviews of prediction Modelling Studies (CHARMS), and the methodological quality and risk of bias will be assessed using the Prediction Model Risk Of Bias Assessment Tool (PROBAST).The results will be synthesised narratively. A meta-analysis using a random-effects model will be conducted if at least five external validation studies are available for the same prediction model.Ethics and dissemination This research is based exclusively on published studies and does not involve the collection of primary data collection from patients. Therefore, ethical approval is not required. Findings will be disseminated through publications in peer-reviewed journals and presentations at national and international conferences.PROSPERO registration number CRD42024579524.
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spelling doaj-art-3d29b9baf7804b7f8bd7c6093756d94f2025-08-20T03:52:32ZengBMJ Publishing GroupBMJ Open2044-60552025-04-0115410.1136/bmjopen-2024-093771Predictive modelling methods of hospital readmission risks for patients with chronic obstructive pulmonary disease (COPD): a systematic review protocolMaude Laberge0Paolo Landa1André Côté2Balkissa Tonde3Metogara Mohamed Traore41 Operations and Decision Systems, Universite Laval Faculte des sciences de l`administration, Quebec City, Quebec, CanadaDepartment of Operations and Decision Systems, Université Laval, Quebec, Quebec, CanadaCentre de recherche du CHU de Québec-Université Laval, Quebec, Quebec, CanadaDepartment of Operations and Decision Systems, Université Laval, Quebec, Quebec, CanadaVitam, Centre de recherche en santé durable - Université Laval, Quebec, Quebec, CanadaIntroduction Chronic obstructive pulmonary disease (COPD) is a significant chronic respiratory condition characterised by persistent airway obstruction, leading to substantial morbidity and mortality worldwide. Patients with COPD frequently experience hospital readmissions shortly after discharge, mainly due to acute exacerbations. This review aims to identify and synthesise the reported performance metrics and methodological limitations of different predictive modelling methods for hospital readmissions in COPD patients.Method and analysis This protocol adheres to the Preferred Reporting Items for Systematic reviews and Meta-Analysis Protocols (PRISMA-P) guidelines. The review will include studies that develop or validate predictive models for hospital readmissions in COPD patients. A comprehensive search will be conducted across PubMed, Embase, Cochrane Library, IEEE Xplore, Web of Science and Google Scholar using predefined keywords. Eligible studies will include those utilising any predictive modelling method, focusing on unplanned readmissions within specified timeframes (30, 60 or 90 days). Two independent reviewers will screen titles, abstracts and full texts, selecting studies based on predefined inclusion criteria.Data extraction will be conducted based on the CHecklist for critical Appraisal and data extraction for systematic Reviews of prediction Modelling Studies (CHARMS), and the methodological quality and risk of bias will be assessed using the Prediction Model Risk Of Bias Assessment Tool (PROBAST).The results will be synthesised narratively. A meta-analysis using a random-effects model will be conducted if at least five external validation studies are available for the same prediction model.Ethics and dissemination This research is based exclusively on published studies and does not involve the collection of primary data collection from patients. Therefore, ethical approval is not required. Findings will be disseminated through publications in peer-reviewed journals and presentations at national and international conferences.PROSPERO registration number CRD42024579524.https://bmjopen.bmj.com/content/15/4/e093771.full
spellingShingle Maude Laberge
Paolo Landa
André Côté
Balkissa Tonde
Metogara Mohamed Traore
Predictive modelling methods of hospital readmission risks for patients with chronic obstructive pulmonary disease (COPD): a systematic review protocol
BMJ Open
title Predictive modelling methods of hospital readmission risks for patients with chronic obstructive pulmonary disease (COPD): a systematic review protocol
title_full Predictive modelling methods of hospital readmission risks for patients with chronic obstructive pulmonary disease (COPD): a systematic review protocol
title_fullStr Predictive modelling methods of hospital readmission risks for patients with chronic obstructive pulmonary disease (COPD): a systematic review protocol
title_full_unstemmed Predictive modelling methods of hospital readmission risks for patients with chronic obstructive pulmonary disease (COPD): a systematic review protocol
title_short Predictive modelling methods of hospital readmission risks for patients with chronic obstructive pulmonary disease (COPD): a systematic review protocol
title_sort predictive modelling methods of hospital readmission risks for patients with chronic obstructive pulmonary disease copd a systematic review protocol
url https://bmjopen.bmj.com/content/15/4/e093771.full
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