Susac's Syndrome in a Patient Diagnosed with MS for 20 Years: A Case Report
Susac’s syndrome is an uncommon neurologic disorder of unknown cause. It has been described as a clinical triad of encephalopathy, hearing loss, and branch retinal artery occlusions. Clinically the diagnosis is difficult when the patient presents only a portion of a triad. We present a case with vis...
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| Format: | Article |
| Language: | English |
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Wiley
2014-01-01
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| Series: | Case Reports in Neurological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2014/214648 |
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| author | Bijen Nazliel Asli Akyol Hale Zeynep Batur Caglayan Irem Yildirim-Capraz Ceyla Irkec |
| author_facet | Bijen Nazliel Asli Akyol Hale Zeynep Batur Caglayan Irem Yildirim-Capraz Ceyla Irkec |
| author_sort | Bijen Nazliel |
| collection | DOAJ |
| description | Susac’s syndrome is an uncommon neurologic disorder of unknown cause. It has been described as a clinical triad of encephalopathy, hearing loss, and branch retinal artery occlusions. Clinically the diagnosis is difficult when the patient presents only a portion of a triad. We present a case with vision loss and sensorineural deafness and who had been diagnosed with MS for 20 years. Susac’s syndrome is presumed to be an autoimmune endotheliopathy. Neurologic symptoms and signs are diffuse and multifocal, acute or subacute in onset, and progress during the active phase of the disease. In some patients the onset was stroke like and in others that of subacute dementia. Headache, often with migrainous features, was a prominent feature initially in more than one half of the patients. A high index of suspicion leading to correct diagnosis and early appropriate therapy may reduce the permanent sequel seen with this disease. Misdiagnosis is common. In patients in whom diagnosis and treatment are delayed permanent morbidity is higher in terms of visual loss, hearing loss, and neurologic debility. In patients in whom rapid diagnosis has led to early administration of immunosuppressive therapy, recovery can be almost complete. |
| format | Article |
| id | doaj-art-3d25f4cc42b44fa29d8b0f688443c2a0 |
| institution | OA Journals |
| issn | 2090-6668 2090-6676 |
| language | English |
| publishDate | 2014-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Neurological Medicine |
| spelling | doaj-art-3d25f4cc42b44fa29d8b0f688443c2a02025-08-20T02:39:08ZengWileyCase Reports in Neurological Medicine2090-66682090-66762014-01-01201410.1155/2014/214648214648Susac's Syndrome in a Patient Diagnosed with MS for 20 Years: A Case ReportBijen Nazliel0Asli Akyol1Hale Zeynep Batur Caglayan2Irem Yildirim-Capraz3Ceyla Irkec4Department of Neurology, Faculty of Medicine, Gazi University, 06500 Ankara, TurkeyDepartment of Neurology, Faculty of Medicine, Gazi University, 06500 Ankara, TurkeyDepartment of Neurology, Faculty of Medicine, Gazi University, 06500 Ankara, TurkeyDepartment of Neurology, Faculty of Medicine, Gazi University, 06500 Ankara, TurkeyDepartment of Neurology, Faculty of Medicine, Gazi University, 06500 Ankara, TurkeySusac’s syndrome is an uncommon neurologic disorder of unknown cause. It has been described as a clinical triad of encephalopathy, hearing loss, and branch retinal artery occlusions. Clinically the diagnosis is difficult when the patient presents only a portion of a triad. We present a case with vision loss and sensorineural deafness and who had been diagnosed with MS for 20 years. Susac’s syndrome is presumed to be an autoimmune endotheliopathy. Neurologic symptoms and signs are diffuse and multifocal, acute or subacute in onset, and progress during the active phase of the disease. In some patients the onset was stroke like and in others that of subacute dementia. Headache, often with migrainous features, was a prominent feature initially in more than one half of the patients. A high index of suspicion leading to correct diagnosis and early appropriate therapy may reduce the permanent sequel seen with this disease. Misdiagnosis is common. In patients in whom diagnosis and treatment are delayed permanent morbidity is higher in terms of visual loss, hearing loss, and neurologic debility. In patients in whom rapid diagnosis has led to early administration of immunosuppressive therapy, recovery can be almost complete.http://dx.doi.org/10.1155/2014/214648 |
| spellingShingle | Bijen Nazliel Asli Akyol Hale Zeynep Batur Caglayan Irem Yildirim-Capraz Ceyla Irkec Susac's Syndrome in a Patient Diagnosed with MS for 20 Years: A Case Report Case Reports in Neurological Medicine |
| title | Susac's Syndrome in a Patient Diagnosed with MS for 20 Years: A Case Report |
| title_full | Susac's Syndrome in a Patient Diagnosed with MS for 20 Years: A Case Report |
| title_fullStr | Susac's Syndrome in a Patient Diagnosed with MS for 20 Years: A Case Report |
| title_full_unstemmed | Susac's Syndrome in a Patient Diagnosed with MS for 20 Years: A Case Report |
| title_short | Susac's Syndrome in a Patient Diagnosed with MS for 20 Years: A Case Report |
| title_sort | susac s syndrome in a patient diagnosed with ms for 20 years a case report |
| url | http://dx.doi.org/10.1155/2014/214648 |
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